Liquid-Phase Detection of Biological Targets with Magnetic Marker and Superconducting Quantum Interference Device
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概要
- 論文の詳細を見る
Liquid-phase detection of biological targets utilizing magnetic marker and superconducting quantum interference device (SQUID) magnetometer is shown. In this method, magnetic markers are coupled to the biological targets, and the binding reaction between them is detected by measuring the magnetic signal from the bound markers. Detection can be done in the liquid phase, i.e., we can detect only the bound markers even in the presence of unbound (free) markers. Since the detection principle is based on the different magnetic properties between the free and bound markers, we clarified the Brownian relaxation of the free markers and the Neel relaxation of the bound markers. Usefulness of the present method is demonstrated from the detection of the biological targets, such as biotin-coated polymer beads, IgE and Candida albicans.
- （社）電子情報通信学会の論文
- 2009-03-01
著者
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濱崎 直孝
九州大学大学院医学研究院臨床検査医学
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濱崎 直孝
九州大学医学系、臨床検査医学
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TSUKAMOTO Akira
Advanced Research Laboratory, Hitachi, Ltd.
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Tsukamoto Akira
Advanced Research Laboratory Hitachi Ltd.
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Hamasaki Naotaka
九州大学 大学院医学研究院臨床化学
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YOSHINAGA Kohji
Department of Applied Chemistry, Kyushu Institute of Technology
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Yokosawa K
Kyushu Inst. Of Technol. Kitakyushu‐shi Jpn
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Kandori Akihiko
Advanced Research Laboratory Hitachi Ltd.
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Tsukamoto A
Advanced Research Laboratory Hitachi Ltd.
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ENPUKU Keiji
Research Institute of Superconductor Science and Systems, Kyushu University
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SUGIMOTO Yuki
Research Institute of Superconductor Science and Systems, Kyushu University
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TAMAI Yuya
Research Institute of Superconductor Science and Systems, Kyushu University
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MIZOGUCHI Takako
Advanced Research Laboratory, Hitachi Ltd.
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USUKI Naoki
R and D Division, Hitachi Maxell Ltd.
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KANZAKI Hisao
R and D Division, Hitachi Maxell Ltd.
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SUGIURA Yoshinori
Plastic Products Division, INOAC Corporation
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KUMA Hiroyuki
Faculty of Pharmaceutical Sciences, Nagasaki International University
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HAMASAKI Naotaka
Faculty of Pharmaceutical Sciences, Nagasaki International University
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Kuma H
The Authors Are With The Department Of Clinical Chemistry And Laboratory Medicine Kyushu University
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濱崎 直孝
九州大学大学院医学研究院臨床分子医学
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Enpuku K
Kyushu Univ. Fukuoka Jpn
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Enpuku Keiji
Research Institute Of Superconductor Science And Systems Kyushu University
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Enpuku Keiji
Department Of Electronic Device Engineering Kyushu University
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濱崎 直孝
九州大学大学院医学研究院臨床検査医学分野
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Hamasaki Naotaka
Faculty Of Pharmaceutical Sciences Nagasaki International University
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Hamasaki Naotaka
Department Of Clinical Chemistry And Laboratory Medicine Kyushu University Graduate School Of Medica
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Sugiura Yoshihisa
Semiconductor Device Engineering Laboratory Toshiba Corporation
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Tamai Yuya
Research Institute Of Superconductor Science And Systems Kyushu University
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Usuki Naoki
R And D Division Hitachi Maxell Ltd.
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Sugimoto Yuki
Research Institute Of Superconductor Science And Systems Kyushu University
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Kanzaki Hisao
R And D Division Hitachi Maxell Ltd.
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Kandori Akihiko
Central Research Laboratory Hitachi Ltd.
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Yoshinaga Kohji
Department Of Applied Chemistry Faculty Of Engineering Kyushu Institute Of Technology
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Kuma Hiroyuki
Faculty Of Pharmaceutical Sciences Nagasaki International Univ
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Mizoguchi Takako
Advanced Research Laboratory Hitachi Ltd.
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Hamasaki Naotaka
Department Of Clinical Chemistry And Laboratory Medicine Graduate School Of Medical Sciences Kyushu
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Hamasaki Naotaka
Dept Of Clinical Chemistry And Laboratory Medicine Graduate School Of Medical Sciences Kyushu Univ
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Kandori Akihiko
Advanced Research Laboratory Hitachi Ltd
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