A New Double-Stranded RNA Binding Protein (DRBP-120) Is Associated with Double-Stranded RNA-Activated Protein Kinase (PKR)
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概要
- 論文の詳細を見る
Double-stranded RNA-activated protein kinase (PKR) plays an important role in interferon-induced antiviral responses, and is also involved in intracellular signaling pathways, including the apoptosis, proliferation, and transcription pathways. In this study, a new 120-kDa PKR-associated protein designated double-stranded RNA binding protein (DRBP)-120 was identified using co-immunoprecipitation with anti-PKR antiserum and two-dimensional electrophoresis. Furthermore, DRBP-120 is a double-stranded RNA (dsRNA)-binding protein, and it was detected in both the cytoplasm and the nucleus of HeLa cells associated with PKR.
- 社団法人 日本農芸化学会の論文
- 2006-07-23
著者
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Yamashita Tetsuro
Department Of Agro-bioscience Faculty Of Agriculture Iwate University
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Taira Hideharu
Department Of Agro-bioscience Faculty Of Agriculture Iwate University
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Watanabe Shuji
Department Of Physiology School Of Medicine Iwate Medical University
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Watanabe Shuji
Department Of Physics Nagoya University
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WATANABE Shuji
Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui
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