A Fermented Grain Food Product Extract Ameliorates Tumor Promoter-Induced Skin Oxidative Stress
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概要
- 論文の詳細を見る
We demonstrated that a dietary supplement, Antioxidant Biofactor (AOB®), a fermented grain food, inhibits phorbol ester (TPA)-induced inflammatory responses. Pretreatment of mouse skin with ethyl acetate extract of AOB (0.5mg) significantly attenuated the hydrogen peroxide level in mouse skin without inhibition of edema formation. Also, exposure of AOB extract to differentiated HL-60 cells resulted in dose-dependent inhibition of TPA-induced superoxide generation, which was stronger than those of the raw materials of AOB. Our results suggest that AOB is effective for prevention of skin oxidative stress.
- 社団法人 日本食品科学工学会の論文
- 2005-12-01
著者
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Nakamura Yoshimasa
高崎健康福祉大学 健康栄養学科
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Osawa Toshihiko
Laboratory Of Food And Biodynamics Nagoya University Graduate School Of Bioagricultural Sciences
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Osawa Toshihiko
Laboratory Of Food And Bio-dynamics Nagoya University
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Nakamura Yoshimasa
Laboratory Of Food And Biodynamics Nagoya University Graduate School Of Bioagricultural Sciences
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