Isolation of Mutagenic β-Carboline Derivatives after Nitrite Treatment of Maillard Reaction Mixtures and Analysis of These Compounds from Foodstuffs and Human Urine
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概要
- 論文の詳細を見る
Mixtures of carbohydrate decomposition products and L-tryptophan were incubated at pH 7.0 and 37 °C for 4 weeks. These mixtures exhibited mutagenic activity toward S. typhimurium TA 100 without metabolic activation after a nitrite treatment at pH 4.0. Four β-carboline derivatives were isolated as premutagens from mixtures of methylglyoxal and furfural. These premutagens were also found to be contained in daily foodstuffs and human urine samples.
- 社団法人 日本農芸化学会の論文
- 2005-11-23
著者
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Kinae Naohide
Department Of Food And Nutritional Sciences Graduate School Of Nutritional And Environmental Science
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KANAMORI Hisayuki
Hiroshima Prefectural Institute of Public Health and Environment
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Masuda Shuichi
Department Of Biological Science Faculty Of Science Hiroshima University
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Masuda Shuichi
Department Of Food And Nutritional Sciences Graduate School Of Nutritional And Environmental Science
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Kanamori Hisayuki
Hiroshima Prefectural Institute Of Public Health And Environment Center
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Kanamori Hisayuki
Hiroshima Prefectural Health Environment Center
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