インドネシアとタイにおけるカニクイザル視物質遺伝子多型の調査報告

概要

論文の詳細を見る
Old World primates have trichromatic vision because they have three types of cone photoreceptors, each of which is maximally sensitive to long (L)-, middle (M)- and short (S)- wavelengths of light. Although a proportion of human males (about 8 % of Caucasians, for example) have X-chromosome-linked color-vision abnormalities, no non-human Old World primates had been found to be color-vision defective to date. However, our molecular genetic analysis showed the existence of male protanopes and female heterozygotes among the long-tailed macaques in Pangandaran National Park, Indonesia (Onishi et al., 1999). The genome of male protanopes contains a single hybrid gene consisting of exons 1 to 4 of the L-photopigment gene and exons 5 and 6 of the M-photopigment gene (L4M5). The absorbance spectrum of L4M5 photopigment was very close to that of M-photopigment. We confirmed the phenotypes of these monkeys by electroretinogram (ERG) flicker photometry (Hanazawa et al., 2001) and by a pattern discrimination task with modified Ishihara pseudo-isochromatic plates (Mikami et al., 2001). The frequency of protanopes in this species was 0.4 %, much lower than in humans. No dichromatic monkeys were found in other macaque species (Onishi et al., 2002). We surveyed long-tailed macaques in Pangandaran National Park, 4 times between 1998 and 2002. This genotype was restricted to 3 neighboring groups among 8 groups in this area. We further surveyed variations of the long- and middle-wavelength-sensitive opsin genes in west and central Jawa, and in southern Thailand. We found another type of hybrid gene in west Jawa and multiple M opsin genes in southern Thailand. In both cases, those genotypes were restricted to each respective area. These results must be helpful to understand the evolution of color vision in primates.
日本霊長類学会の論文
2004-12-31

インドネシアとタイにおけるカニクイザル視物質遺伝子多型の調査報告

スポンサーリンク

概要

著者

関連論文

スポンサーリンク