Thymic Squamous Cell Carcinoma Producing Parathyroid Hormone-related Protein and CYFRA 21-1

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概要

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• A 54-year-old man was admitted to our hospital because of dyspnea. Radiographic examination showed an anterior mediastinal mass and pericardial effusion. Serum calcium and parathyroid hormone-related protein (PTHrP) levels were elevated, and serum CYFRA 21-1 level was extremely high. Results of percutaneous needle biopsy under computed tomography guidance led to a diagnosis of moderately differentiated squamous cell carcinoma. Immunohistological staining showed the tumor cells to be positive for PTHrP and cytokeratin monoclonal antibodies. Postmortem findings were considered to indicate thymic carcinoma. Thymic carcinoma is rare, but our case indicates that thymic squamous cell carcinoma can be identified in terms of paraneoplastic hypercalcemia.

• 社団法人　日本内科学会の論文
• 2004-06-01

著者

• KOIZUMI TOMONOBU

  First Department of Internal Medicine, Shinshu University School of Medicine

• KUBO KEISHI

  First Department of Internal Medicine, Shinshu University School of Medicine

• HANAOKA Masayuki

  First Department of Internal Medicine, Shinshu University School of Medicine

• Kubo Keishi

  First Department Of Internal Medicine Dhinshu University School Of Medicine

• Kubo Keishi

  The Department Of Neurology Nagano Red Cross Hospital

• YAMAGUCHI Shinji

  First Department of Internal Medicine, Shinshu University School of Medicine

• Yamaguchi Shinji

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Koizumi Tomonobu

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Kaneki Toshimichi

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Kubo Keishi

  The First Department Of Internal Medicine Shinshu University Hospital

• YOSHIIKE Fumiaki

  First Department of Internal Medicine, Shinshu University School of Medicine

• YONEYAMA Ayako

  First Department of Internal Medicine, Shinshu University School of Medicine

• KOMATU Michiharu

  First Department of Internal Medicine, Shinshu University School of Medicine

• EDA Seiichirou

  Internal Medicine, Matsumoto Kyouritsu Hospital

• Yoneyama Ayako

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Eda Seiichirou

  Internal Medicine Matsumoto Kyouritsu Hospital

• Kumagai Toshiko

  First Department Of Medicine Shinshu University School Of Medicine

• Haniuda Masayuki

  The Second Department Of Surgery Shinshu University

• Kubo Keishi

  The First Department Of Internal Medicine Shinshu University

• Tsushima Kenji

  The First Department Of Internal Medicine Shinshu University School Of Medicine

• Komatu Michiharu

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Yoshiike Fumiaki

  First Department Of Internal Medicine Shinshu University School Of Medicine

• Kubo K

  Department Of Pulmonary And Infectious Diseases Shinshu University Hospital

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