Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment for Drug-Induced Severe Respiratory Failure: Report of Three Cases
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概要
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The effects of direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP) treatment for acute exacerbation of interstitial pneumonia have been reported. Here, we report 3 severe cases of drug-induced interstitial lung disease (DI-ILD) that were treated with PMX-DHP. Two DI-ILD cases were caused by methotrexate, and the third case was caused by the herbal medicine sanmotsu-ogon-to. The arterial oxygen tension/inspiratory oxygen fraction ratio improved during PMX-DHP treatment in all 3 patients. Finally, 2 patients survived and 1 died. The study findings indicate that PMX-DHP treatment is a viable option for the management of acute respiratory failure in patients with DI-ILD.
著者
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Kubo Keishi
The First Department of Internal Medicine, Shinshu University School of Medicine
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Yokoyama Toshiki
The First Department of Internal Medicine, Shinshu University School of Medicine
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Kubo Keishi
The First Department Of Internal Medicine Shinshu University
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Tsushima Kenji
The First Department Of Internal Medicine Shinshu University School Of Medicine
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Yamamoto Hiroshi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Agatsuma Toshihiko
The First Department of Internal Medicine, Shinshu University School of Medicine
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Ito Michiko
The First Department of Medicine, Shinshu University School of Medicine
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Kozumi Tomonobu
The First Department of Internal Medicine, Shinshu University School of Medicine
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Yamamoto Hiroshi
The First Department of Internal Medicine, Shinshu University School of Medicine
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