Biological Activity of a Cyclic Peptide from Laminin α1 Chain Loop Region

スポンサーリンク

概要

• 論文の詳細を見る
• 2004-03-01

著者

• FUJII Nobutaka

  Graduate School of Pharmaceutical Sciences, Kyoto University

• OISHI Shinya

  Graduate School of Pharmaceutical Sciences, Kyoto University

• Oishi Shinya

  Graduate School Of Pharmaceutical Sciences Kyoto University

• Oishi Shinya

  Laboratory Of Medicinal Chemistry Ccr Nci Nih

• NOMIZU Motoyoshi

  Graduate School of Environmental Earth Science, Hokkaido University

• YOKOYAMA Fumiharu

  Graduate School of Environmental Earth Science, Hokkaido University

• SUZUKI Nobuharu

  Graduate School of Environmental Earth Science, Hokkaido University

• Nishi Norio

  Graduate School Of Environmental Earth Science Hokkaido University

• Nishi Norio

  Division Of Bioscience Graduate School Of Environmental Earth Science Hokkaido University

• Fujii Nobutaka

  Graduate School Of Pharmaceutical Sciences Kyoto University

• YASUI Toshio

  Graduate School of Environmental Earth Science, Hokkaido University

• Nomizu M

  School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences

• 野水 基義

  Tokyo University Of Pharmacy And Life Sciences

• Yasui Toshio

  Graduate School Of Environmental Earth Science Hokkaido University

• Suzuki Nobuharu

  Laboratory Of Clinical Biochemistry School Of Pharmacy Tokyo University Of Pharmacy And Life Science

• Suzuki Nobuharu

  Graduate School Of Environmental Earth Science Hokkaido University

• Nishi N

  Hokkaido Univ. Sapporo

• Nomizu Motoyoshi

  Graduate School Of Environmental Earth Science Hokkaido University

• Yokoyama Fumiharu

  Graduate School Of Environmental Earth Science Hokkaido University

• Nishi Norio

  Graduate School of Environmental Earth Science, Hokkaido University

関連論文

• Stereodivergent Synthesis of Chiral 2-Alkenylaziridines : Palladium(0)-Catalyzed 2,3-cis-Selective Aziridination and Base-Mediated 2,3-trans-Selective Aziridination
• Synthesis of a CC Chemokine, vMIP-II, Encoded by Kaposi's Sarcoma-Associated Herpesvirus and Its Biological Activity
• Development of Chemical Probes for the Chemokine Receptor CXCR4 Involving Radiolabeled T140 Analogs
• Development of the Chemokine Receptor CXCR4 Antagonists as Multi-Pharmaceutical Agents Involving a New Class of Low Molecular Weight Antagonists
• P-423 Structure-Activity Relationship Studies on Cyclic Peptide-Based CXCR4 Antagonists
• Synthesis and Biological Evaluation of Peptidomimetic Analogs of the CXCR4 Antagonist FC131
• The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases Including AIDS, Cancer and Rheumatoid Arthritis
• New Leads of Low Molecular Weight CXCR4 Antagonists Based on Enhancement of the T140-based Pharmacophores
• A New Strategy for Molecular-size Reduction of Bioactive Peptide, Using Two Orthogonal Libraries of Cyclic peptides
• CXCR4 Antagonists Identified as Anti-Cancer-Metastatic Agents
• Synthesis of Novel Anti-HIV Peptides Based on a CXCR4 Antagonist, T140, and Their SAR Study
• Development of Specific CXCR4 Inhibitors Based on an Anti-HIV Peptide, T140, and Their Structure-Activity Relationships Study
• Increase of R5 HIV-1 infection and CCR5 expression in T cells treated with high concentrations of CXCR4 antagonists and SDF-1
• HIV-cell Fusion Inhibitors Targeted to the HIV Second Receptor : T22 and Its Downsized Analogs with High Activity
• Preparation and Biological Activities of a Bivalent Poly(Ethylene Glycol) Hybrid Containing an Active Site and Its Synergistic Site of Fibronectin
• Helix Inducible Motifs Affect Helicity and Bioactivity of Anti-HIV Peptides
• Synthesis of CXCR4 Antagonists, T140 Derivatives with Improved Biostability, and Their SAR Study
• Development of Fusion-inhibiting Anti-HIV-1 Peptides Based on the Structure of Molecular Complex Involved in HIV-1-cell Fusion
• Application of β-Branched Allylglycine Equivalents to Macrocyclic Grb2 SH2 Domain-Binding Inhibitors
• Efficient Synthesis of Cyclic RGD Pseudopeptide with (E)-Alkene Dipeptide Isostere and Its Biological Activity
• Synthesis and Application of Novel Fluorescence-Labeled CXCR4 Antagonists
• Design and Synthesis of Highly Active Anti-HIV Peptide Based on Gp41-C34 Peptide
• Bioactivity of Cyclic Analogs of a Syndecan-Binding Peptide Derived from the Human Laminin α3 Chain LG4 Module
• Peptide-Conjugated Chitosan Membranes : New Biomedical Materials as Extracellular Matrix Mimetics
• Identification of Heparin Binding Sites in the Laminin α2 Chain LG4-5 Module
• P-467 Structure-activity relationship study on GPR54 agonists
• Synthesis of Alkene Type Dipeptide Isosteres and Their Use to Probe the Structural Requirements of Peptide Transporter (PEPT1)
• Structure-Activity Relationship Study on hOT7T175 Agonist with RW-Amide
• Synthesis of (Z)-Alkene cis-Ala-Pro Mimetics Using Organocopper Reagents
• Endeavors for Highly Stereoselective Synthesis of Functionalized Fluoroalkene Dipeptide Isosteres
• Stereoselective Synthesis of Diketopiperazine Mimetics as Promising Scaffolds for Drug Discovery Utilizing Organocopper-Mediated anti-S_N2' Reaction
• Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type Dipeptide Isosteres and their Application to a Cyclic RGD Peptide
• Synthesis of ψ[(E)-CMe=CMe]- and ψ[(E)-CMe=CH]-type Alkene Dipeptide Isosteres from a Chiral Amino Acid
• Properties of Intracellular Fragment Peptides of Mouse Prostaglandin E_2 Receptor EP3 Isoform
• Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus(Virology)
• Synthetic Studies of Tokaramide A and Miraziridine A Isolated from Marine Sponge Theonella aff. mirabilis
• A Bivalent Poly (ethylene glycol) Hybrid Containing an Active Site (RGD) and a Synergistic Site of Fibronectin
• Structure-Function Relationship of Molecular Chaperone Protein -Nucleoplasmin-
• Conjugation of Laminin Derived Cell Adhesive Peptides on a Chitosan Membrane and Their Biological Activity
• Effect of Nucloeplasmin on Stability of Nucleosome Structure
• Large-Scale Production of Ba^-Alginate-Coated Vesicles of Carbon Nanofibers for DNA-Interactive Pollutant Elimination
• Specific Fluorescence Labeling of Membrane Receptors in Living Cells using Coiled-coil Tag
• Screening of Amyloidogenic Peptides in Laminin-1
• Neurite Outgrowth Promoting Sites on the Laminin Alpha 3 Chain
• Cell Adhesive and Heparin Binding Sites on the Laminin Alpha Chain G Domains
• Identification of Biologically Active Sequences on the Laminin Alpha Chain G Domains
• Identification of Cell Adhesive Sites on the Laminin Alpha Chain Domain VI
• Effect of KAFDITYVRLK(C-16), a Laminin Gamma 1 Chain Peptide, to Tumor Cell Adhesion and Metastasis
• Identification of Biologically Active Peptides in Laminin-1
• Fluoroalkene Skeleton as a Peptide Bond Mimetic : Its Scope and Limitations
• Establishment and Clinical Application of an Enzyme Immunoassay for Metastin to Determination of the Human Plasma Levels
• A Novel Oxazolidine Linker for the Synthesis of Peptide Aldehydes
• Structure-Activity Relationship Studies on GPR54 Agonists
• Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetrapeptide-scaffolds
• Cyclic Analogs Derived from Laminin Enhanced the Biological Activities
• Biological Activity of a Cyclic Peptide from Laminin α1 Chain Loop Region
• Identification of Biological Active Sites in the Laminin α5 Chain LG4-5 Tandem
• Effect of Homologous Loop Regions in Human Laminin α Chain LG4 Domain on Cell Morphology and Proliferation
• Biological Activities of the Loop Structure Regions in the Laminin Alpha Chain G Domains
• IDENTIFICATION OF HEPARIN-DEPENDENT CELL ADHESION SITE WITHIN LAMININ α4 CHAIN C-TERMINAL GLOBULAR DOMAIN
• Peptide Mapping of Biologically Active Sequences in the Laminin Alpha 4 Chain G Domain
• Synthesis and Application of Novel Phosphotyrosyl Mimetics to Grb2 SH2 Domain-Binding Inhibitors
• Synthesis of (Z)-Alkene cis-Xaa-Pro Type Dipeptide Isosteres Using Organocopper-Mediated Anti-S_N2' Reactions
• 4-(Dimethylamino)phenacyl Group : New Photoremovable Protecting Group for Amines and Carboxylic Acids
• Acid-catalyzed Ring-opening Reactions of β-Aziridinyl-α, β-enoates and Their Application
• Structure-Activity Relationship Study of CXCR4 Antagonists on the Cyclic Pentapeptide Scaffold : Identification of New Pharmacophore Moieties
• Application of Ring Closing Olefin Metathesis to the Conformational Restriction of Biologically Active Peptide. Part 1
• Identification of Novel HIV-1 Fusion Inhibitors by Template-Assisted Peptide Aldehyde Ligation
• Structure Activity Relationship Study of the Helix-inducible Motifs in HIV Fusion Inhibitors
• X-ray Crystallographic Study of the HIV-1 Fusion Inhibitor against the Drug-Resistant N43D Variant
• Bioorganic Synthesis of End-capped HIV-1 Fusion Inhibitor SC35EK
• Stereoselective Synthesis of CF_2 or CHF-Substituted Phosphoamino Acids and Their Incorporation into Peptides
• Synthesis of β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere and their Structure-activity Relationship Studies
• Interactions between Local Anesthetics and Na^+ Channel Inactivation Gate Peptides in Phosphatidylserine Suspensions as Studied by ^1H-NMR Spectroscopy
• Translocation of Basic Peptides through Human Cell Membranes
• Conformational Study of the Tandem Repeat Sequence in RNA Polymerase II by Circular Dichroism Spectroscopy
• Development of Novel GPR54 Agonists with Resistance to Degradation by MMP
• Diastereoselective Synthesis of (Z)-Fluoroalkene Dipeptide Isostere and the Application to a HIV Membrane Fusion Inhibitor
• Diastereoselective Synthesis of Trifluoromethylalkene Dipeptide Isosteres Based on Nucleophilic Trifluoromethylation
• Synthesis of Peptide Thioester Based on N-S Acyl Transfer Utilizing Cysteine-derived Acyloxazolidinone with Practical Application to Peptide Synthesis
• Effect of DNA on Collagen Fibrillogenesis
• New Strategy for The Synthesis of Aspartyl Protease Inhibitor Based on "Aza-Payne Rearrangement"
• Synthetic Studies on 7TM-GPCR (I) : Lipid Bilayer Assisted Membrane Peptide Ligation
• Utility of Plasma Bioactive Peptides Levels as Biomarkers
• Effect of the Substituent Groups of SCM-Chitin-RGDS Conjugate on Inhibitory Activity of Tumor Metastasis
• Synthesis of (E)-Alkene trans-Xaa-Pro Mimetics Using Organocopper Reagents
• Stereoselective Synthesis of Peptidomimetics with Hydroxyethylamine Dipeptide Isosteres Utilizing Aza-Payne Rearrangement and O, N-Acyl Transfer Reactions
• Functional Sites in the Laminin Alpha Chains
• Apoptosis Induction of Leukemia Cells by The Integrin-Activating Peptide Derived from Tenascin-C
• Gap-Fill Process of Shallow Trench Isolation for 0.13 μm Technologies
• Functional Peptide Fibrils as Bio-medical Materials
• Stereoselective Synthesis of Tyr-Orn Type Alkene Dipeptide Isosteres and Their Application to Bioactive Peptides
• Functional Characterization of Kisspeptin Receptor Ligands : Activation of Neuropeptide FF Receptors
• Identification of Cell Binding Sites in the Laminin Alpha 5 chain G-Domain by Systematic Screening of Synthetic Peptides
• Biologically Active Sequences in Laminin, a Multifunctional Extracellular Matrix Protein
• Synthetic Studies on Coibamide A
• High-Throughput Turbidimetric Screening for Heparin-Neutralizing Agents and Low-Molecular-Weight Heparin Mimetics
• Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats
• Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows
• Synthesis and Investigation of Novel Metal Complexes of Deferriferrichrysin

もっと見る 閉じる

スポンサーリンク