Low-Titer Cold Agglutinin Disease with Systemic Sclerosis
スポンサーリンク
概要
- 論文の詳細を見る
A 60-year-old woman with systemic sclerosis (SSc) was admitted because of severe anemia and Raynaud’s phenomenon. Her anemia was associated with a low serum haptoglobin level and positive results of direct Coomb’s tests, which indicated the presence of autoimmune hemolysis. Other laboratory investigations revealed positive anti-nuclear antibodies, anti-topoisomerase antibody, cold agglutinins, as well as low serum levels of IgM, C3, C4 and CH50. Bone marrow aspiration showed discrete hyperplasia of the erythropoietic system. She was diagnosed as low-titer cold agglutinin disease rousing secondarily to SSc. The anemia was alleviated with the oral administration of prednisolone. This case emphasized, in terms of pathogenesis, the close association between systemic rheumatic diseases and hematological abnormalities evoked by autoimmunity.
- 社団法人 日本内科学会の論文
- 2004-02-01
著者
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DOI MASAO
Department of Applied Physics, The University of Tokyo
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Morimoto Keiko
Department of Enviromental Health, Faculty of Life Science and Human Technology, Nara Women's Univer
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MAEDA Hiroyuki
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima Uni
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KUWABARA Masao
Department of Internal Medicine, Hiroshima Prefecture Hospital
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Oshima Miki
Department Of Respiratory Medicine And Rheumatology Hiroshima Prefectural Hospital
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Kuwabara Masao
Department Of Internal Medicine Hiroshima Prefectural Hospital Graduate School Of Biomedical Science
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Kuwabara Masao
Department Of Respiratory Medicine And Rheumatology Hiroshima Prefectural Hospital
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Morimoto Keiko
Department Of Enviromental Health Faculty Of Life Science And Human Technology Nara Women's Uni
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Morimoto Keiko
Department Of Respiratory Medicine And Rheumatology Hiroshima Prefectural Hospital
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Doi Masao
Department Of Applied Physics Graduate School Of Engineering The University Of Tokyo:crest Japan Sci
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Doi Masao
Department Of Respiratory Medicine And Rheumatology Hiroshima Prefectural Hospital
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Doi Masao
Department Of Applied Physics Faculty Of Engineering Nagoya University
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Maeda Hiroyuki
Department Of Respiratory Medicine And Rheumatology Hiroshima Prefectural Hospital
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Maeda Hiroyuki
Department Of Civil And Environmental Engineering Faculty Of Engineering National University Corpora
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MAEDA Hiroyuki
Department of Chemistry, Materials Engineering, Kansai University
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MAEDA Hiroyuki
Departhents of Biochemistry and Surgery, Fukui Medical School
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