Analysis of Synergism in Hepatocarcinogenesis Based on Preneoplastic Foci Induction by 10 Heterocyclic Amines in the Rat

スポンサーリンク

概要

• 論文の詳細を見る
• 1996-11-30

著者

• Inada Ken-ichi

  Department Of Pathology Fujita Health University School Of Medicine

• Imai Norio

  Dims Institute Of Medical Science Inc.

• Imai Norio

  Dims医科学研究所

• IMAIDA Katsumi

  Onco-Pathology, Faculty of Medicine, Department of Pathology and Host-Defense, Kagawa University

• ITO Nobuyuki

  Nagoya City University

• IMAI NORIO

  Daiyu-kai Institute of Medical Science

• SHIRAI Tomoyuki

  First Department of Pathology, Nagoya City University Medical School

• HASEGAWA Ryohei

  First Department of Pathology, Nagoya City University Medical School

• Imaida K

  Onco-pathology Faculty Of Medicine Department Of Pathology And Host-defense Kagawa University

• Imaida Katsumi

  国立がんセンター研究所 がん予防基礎研究プロジェクト

• Hasegawa R

  First Department Of Pathology Nagoya City University Medical School

• Imaida Katsumi

  大雄会医科学研究所

• Inada K

  Department Of Pathology Fujita Health University School Of Medicine

• IMAIDA Katsumi

  First Department of Pathology, Nagoya City University Medical School

• Shirai Tomoyuki

  First Department Of Pathology Nagoya City University Medical School

• Hasegawa Ryouhei

  First Department Of Pathology Nagoya City University Medical School

• YOSHIMURA Isao

  Department of Industrial Management and Engineering, Science University of Tokyo

• Hasegawa Ryohei

  First Department Of Pathology Nagoya City University Medical School

• Yoshimura Isao

  Department Of Applied Physics Faculty Of Engineering Nagoya University

• Imaida Katsumi

  First Department Of Pathology Nagoya City University Medical School

• Ito N

  Nagoya City Univ. Nagoya

関連論文

• A twenty eight-day repeated dose toxicity study of black soybean extract in Sprague-Dawley rats
• Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils
• Coexistence of gastric-and intestinal-type endocrine cells in gastric and intestinal mixed intestinal metaplasia of the human stomach
• Immunohistochemically detectable Cdx2 is present in intestinal phenotypic elements in early gastric cancers of both differentiated and undifferentiated types, with no correlation to non-neoplastic surrounding mucosa
• Effect of early eradication on Helicobacter pyloirirelated gastric carcinogenesis in Mongolian gerbils
• Synergistic Promoting Effects of Helicobacter pylori Infection and High-salt Diet on Gastric Carcinogenesis in Mongolian Gerbils
• Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
• Reversibility of Heterotopic Proliferative Glands in Glandular Stomach of Helicobacter pylori-infected Mongolian Gerbils on Eradication
• Mouse Strain Susceptibility to Diethylnitrosamine Induced Hepatocarcinogenesis Is Cell Autonomous Whereas Sex-susceptibility Is Due to the Micro-environment:Analysis with C3H【tautomer】BALB/c Sexually Chimeric Mice
• New animal model of glandular stomach carcinogenesis in Mongolian gerbils infected with Helicobacter pylori and treated with a chemical carcinogen
• Increased Expression of Sucrase and Intestinal-type Alkaline Phosphatase in Human Gastric Carcinomas with Progression.
• Stable Expression of Glutathione S-transferase P-form mRNA and TGF-α Immunohistochemical Expression are Useful Markers for Identification of Persistent Nodules from an Early Stage in Rat Hepatocarcinogenesis
• N-Methyl-N-nitrosourea Concentration-dependent, Rather than Total Intake-dependent, Induction of Adenocarcinomas in the Glandular Stomach of BALB/c Mice
• Increased Expression of Sucrase and Intestinal-type Alkaline Phosphatase in Human Gastric Carcinomas with Progression
• Dose-dependent Promoting Effects of Catechol on Glandular Stomach Carcinogenesis in BALB/c Mice Initiated with N-Methyl-N-nitrosourea
• Rare Occurrence of ras and p53 Gene Mutations in Mouse Stomach Tumors Induced by N-Methyl-N-nitrosourea
• LACK OF HINOKITIOL (BETA-THUJAPLICIN) CARCINOGENICITY IN F344/DuCrj RATS
• Thirteen-Week Oral Toxicity Study of Dokudami Extract (Houttuynia Cordata Thunb.) in F344/DuCrj Rats
• Dose Dependent Promoting Effects of Hexachlorobenzene on Hepatocarcinogenesis in a Rat Medium-Term Liver Bioassay(Carcinogenicity, Proceedings of the 32nd Annual Meeting)
• Lack of Chemoprevention or Promotion Effects of Docosahexaenoic Acid on Small Intestine, Colon, Liver, Lung, Thyroid, Esophagus, Kidney, and Forestomach Carcinogenesis in a Rat Medium-Term Multi-Organ Carcinogenesis Model
• Evidence of a Threshold Dose for Promotion of Hepatocarcinogenesis by Hexachlorobenzene in a Rat Medium-Term Liver Bioassay
• A MEDIUM-TERM RAT LIVER BIOASSAY FOR RAPID IN VIVO DETECTION OF CARCINOGENIC POTENTIAL OF CHEMICALS
• Dose-related changes in gene expression in the livers of rats treated with sodium Phenobarbital as assessed using a three-dimensional microarray system. (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30t
• One-generation reproductive toxicity study of Fenitrothion in rats. (DEVELOPMENT AND REPRODUCTION) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• Ninety-toxicity study of annatto extract, a natural food color, in rats. (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• LACK OF CARCINOGENIC RISK IN THE PROSTATE WITH TRANSPLACENTAL AND LACTATIONAL EXPOSURE TO BISPHENOL A IN RATS
• A 28-day oral toxicity study of fermentation-derived cellulose, produced by Acetobacter aceti subspecies xylinum, in F344 rats
• Clinicopathological analysis on cancers of autopsy cases in a geriatric hospital
• Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography
• Inhibition of Helicobacter pylori Motility by (+)-Syringaresinol from Unripe Japanese Apricot(Medicinal Chemistry)
• Gastric and intestinal mixed and solely intestinal types of intestinal metaplasia in the human stomach
• Dose-dependent Induction of Both Pepsinogen-altered Pyloric Glands and Adenocarcinomas in the Glandular Stomach of C3H Mice Treated with N-Methyl-N-nitrosourea
• Growth Characteristics in the Initial Stage of Micrometastasis Formation by Bacterial LacZ Gene-tagged Rat Prostatic Adenocarcinoma Cells
• Development of Aberrant Crypt Foci Involves a Fission Mechanism as Revealed by Isolation of Aberrant Crypts
• Cellular differentiation and development of pyloric mucosal metaplasia in the human gall-bladder
• Ninety-day oral toxicity study of rhamsan gum, a natural food thickener produced from Sphingomonas ATCC 31961, in Crl:CD(SD)IGS rats
• An Intratracheal Instillation Bioassay System for Detection of Lung Toxicity Due to Fine Particles in F344 Rats
• Potential Inhibitory Effects of D-Allose, a Rare Sugar, on Liver Preneoplastic Lesion Development in F344 Rat Medium-Term Bioassay(MEDICAL BIOTECHNOLOGY)
• Overexpression of CYP2A6 in human colorectal tumors
• Detection of Carcinogenic and Modifying Potentials by Test Compounds Using a Mouse Lung Carcinogenesis Bioassay
• Dose-dependent Induction of 8-Hydroxyguanine and Preneoplastic Foci in Rat Liver by a Food-derived Carcinogen, 2-Amino-3, 8-dimethylimidazo [4,5-f] quinoxaline, at Low Dose Levels
• A18 RAT WIDE-SPECTRUM INITIATION MULTIPLE ORGAN BIOASSAY MODELS FOR ASSESSING MODIFYING EFFECTS IN CARCINOGENESIS
• DOSE DEPENDENT PROMOTING EFFECTS OF ANTIOXIDANT CHEMICALS ON RAT URINARY BLADDER CARCINOGENESIS WHEN COMBINED WITH UNILATERAL URETER LIGATION
• CARCINOGENICITY OF DIFOLATAN IN B6C3F_1 MICE
• EFFECTS OF PARTIAL HEPATECTOMY AND CARBON TETRACHLORIDE ON THE INDUCTION OF HYPERPLASTIC NODULES IN THE LIVER TREATED WITH N-2-FLUORENYLACETAMIDE
• EFFECTS OF THE CO-MUTAGEN N0RHARMAN IN RATS (The 6th Meeting for the Study of Toxic Effect)
• HISTOPATHOLOGICAL STUDY OF SUBACUTE EFFECTS OF CARBAZOLE IN MICE (The 6th Meeting for the Study of Toxic Effect)
• SUBACUTE TOXICITY STUDY OF N, N'-DIPHENYL-P-PHENYENEDIAMINE IN RATS (The 6th Meeting for the Study of Toxic Effect)
• HEPATO CARCINOGENICITY OF POLYCHLORINATED TERPHENYLS IN ICR MICE AND ITS ENHANCEMENT BY HEXACHLOROBENZENE (The 5th Meeting for the Study of Toxic Effect)
• HISTOPATHOLOGICAL STUDY OF CHRONIC EFFECT OF ETHYLENE CYANOHYDRIN (ECH) ON MALE NICE AND RATS (The 5th Meeting for the Study of Toxic Effect)
• PREVENTION BY NATURAL FOOD ANTHOCYANINS, PURPLE SWEET POTATO COLOR AND RED CABBAGE COLOR, OF 2-AMINO- 1 -METHYL-6-PHENYLIMIDAZO [4,5 -b] PYRIDINE (PhIP)-ASSOCIATED COLORECTAL CARCINOGENESIS IN RATS INITIATED WITH 1,2-DIMETHYLHYDRAZINE
• Dose-dependent Induction of Mammary Carcinomas in Female Sprague-Dawley Rats with 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine
• B-26 ORGAN SPECIFIC EFFECT OF TUMOR DEVELOPMENT BY LOW DOSE COMBINATIONS OF MODIFICATION AGENTS IN WIDE-SPECTRUM CARCINOGENESIS MODEL USING F344 RATS
• Hepatocyte Growth Factor Enhancement of Preneoplastic Hepatic Foci Development in Rats Treated with Diethylnitrosamine and N-Ethyl-N- hydroxyethylnitrosamine
• Decrease of Prostaglandin E_2 and 5-Bromo-2'-deoxyuridine Labeling but Not Prostate Tumor Development by Indomethacin Treatment of Rats Given 3,2'-Dimethyl-4-aminobiphenyl and Testosterone Propionate
• DOSE-DEPENDENT ENHANCEMENT BY THE HORMONE DEHYDROEPIANDROSTERONE OF DIETHYLNITROSAMINE-INITIATED LIVER FOCI DEVELOPMENT IN F344 MALE RATS
• EVALUATION OF CARCINOGENICITY OF PESTICIDES IN A MEDIUMTERM LIVER CARCINOGENICITY BIOASSAY
• 325 Synergistic Enhancement of Glutathione S-Transferase Placental Form-positive Hepatic Foci Development in Diethylnitrosamine-treated Rats by Combined Administration of Five Heterocyclic Amines at Low Doses
• SUBCHRONIC TOXICITY STUDY OF MAGNESIUM CHLORIDE IN B6C3F_1 MICE
• SUBCHRONIC TOXICITY STUDY OF VITAMIN P (METHYL HESPERIDIN) IN B6C3F_1 MICE
• MODIFICATION POTENTIAL OF PESTICIDES AND ENVIRONMENTAL CHEMICALS ON THE INDUCTION OF PRENEOPLASTIC LIVER CELL FOCI IN AN IN VIVO SHORT-TERM ASSAY SYSTEM
• PROMOTIVE EFFECTS OF 1-(3-TRIFLUOROMETHYLPHENYL)-3-(2-HYDROXYETHYL)-QUINAZOLINE-2,4(1H,3H)-DIONE (THQD) ON HEPATOCARCINOGENESIS INITIATED BY DIETHYLNITROSAMINE (DEN) IN F344 RATS
• CHRONIC TOXICITY STUDIES WITH N,N'-DIPHENYL-P-PHENYLENEDIAMINE IN RATS
• EFFECT OF NORHARMAN ON THE INITIATION OF PRENEOPLASTIC LESIONS IN THE LIVER BY ANILINE, ETHIONINE AND Trp-P-1 IN THE RAT
• SUBCHRONIC ORAL TOXICITY STUDY WITH MORPHOLINE OLEIC ACID SALT IN B6C3F_1 MICE
• PROMOTING EFFECTS OF SODIUM L-ASCORBATE ON RAT BLADDER CARCINOGENESIS
• THIRTEEN WEEKS SUBACUTE ORAL TOXICITY STUDY WITH SODIUM ORTHO-PHENYL-PHENATE (OPP-Na) IN B6C3F_1 MICE
• Annatto extract, a carotenoid natural food color, lacks tumor promoting effects in a medium-term liver carcinogenesis bioassay in rats (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• LACK OF SIGNIFICANT ALTERATION IN THE PROSTATE OR TESTIS OF F344 RAT OFFSPRING AFTER TRANSPLACENTAL AND LACTATIONAL EXPOSURE TO BISPHENOL A
• Effect of bisphenol A, an endocrine disruptor, on hepatocarcinogenesis and on reproductive system in medium-term liver bioassay.(GENERAL SESSION BY POSTER PRESENTATION)(ACTIVE OXYGEN ETC)
• RELIABILITY AND PRACTICALITY OF MEDIUM-TERM CARCINOGENESIS BIOASSAYS(WORKSHOP 4 : NEW TECHNOLOGY AND EVALUATIONS OF IN VIVO TOXICITY STUDIES)
• Site-specific Effects of Testosterone Propionate on the Prostate of Rat Pretreated with 3,2'-Dimethyl-4-aminobiphenyl : Dose-dependent Induction of Invasive Carcinomas
• Organ-dependent Modifying Effects of Caffeine, and Two Naturally Occurring Antioxidants α-Tocopherol and n-Tritriacontane-16, 18-dione, on 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) -induced Mammary and Colonic Carcinogenesis in Female F344
• "P-33 Inhibition of development of naturally occuring GST-P positive hepatocytic foci in rats chronically treated with phenolic compounds
• Beef Tallow, but Not Perilla or Corn Oil, Promotion of Rat Prostate and Intestinal Carcinogenesis by 3,2'-Dimethyl-4-aminobiphenyl
• 21S1A-11-1 Carcinogenic Potential of Endocrine Disruptors
• DOSE-DEPENDENT INDUCTION OF CARCINOMAS AND GLUTATHIONE S-TRANSFERASE PLACENTAL FORM NEGATIVE EOSINOPHILIC FOCI IN THE RAT LIVER BY DI(2-ETHYLHEXYL)PHTHALATE AFTER DIETHYLNITROSAMINE INITIATION
• The 1.5 GHz Electromagnetic Near-field Used for Cellular Phones Does Not Promote Rat Liver Carcinogenesis in a Medium-term Liver Bioassay
• MEDIUM-TERM BIOASSAYS AS ALTERNATIVE CARCINOGENICITY TEST
• Analysis of Synergism in Hepatocarcinogenesis Based on Preneoplastic Foci Induction by 10 Heterocyclic Amines in the Rat
• Direct Effects of Testosterone, Dihydrotestosterone and EStrogen on 3,2'-Dimethyl-4-aminobiphenyl-induced Prostate Carcinogenesis in Castrated F344 Rats
• EFFECTS OF A MIXTURE OF ADI DOSES OF 20 PESTICIDES ON RAT HEPATOCARCINOGENESIS
• INHIBITING EFFECTS OF DIETHYLMALEATE OR NH_4Cl ON NaHCO_3, BUT NOT BUTYLATED HYDROXYANISOLE, PROMOTION OF URINARY BLADDER CARCINOGENESIS IN MALE F344 RATS INITIATED WITH N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMINE
• THE EFFECTS OF COFFEE ON LIVER CARCINOGENESIS USING A MEDIUM-TERM BIOASSAY SYSTEM
• EFFECTS OF ACETAMINOPHEN ON LIVER AND URINARY BLADDER CARCINOGENESIS IN F344 RATS
• A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals
• RISK ASSESSMENT OF MIXTURES OF 40 OR 20 PESTICIDES AT ADI DOSES IN A MEDIUM-TERM MULTI-ORGAN CARCINOGENESIS BIOASSAY USING F344 MALE RATS
• Mixed connective tissue disease complicated by pneumatosis cystoides intestinalis and malabsorption syndrome : Case report and literature review
• Appropriate Epitope Retrieval for c-kit Protein Immunostaining in Routinely Prepared Specimens of Gastrointestinal Stromal Tumor
• Immunohistochemical analysis of thymidylate synthase, p16^, cyclin-dependent kinase 4 and cyclin D1 in colorectal cancers receiving preoperative chemotherapy : Significance of p16^- mediated cellular arrest as an indicator of chemosensitivit
• Immunohistochemical Demonstration of Dihydropyrimidine Dehydrogenase in Normal and Cancerous Tissues(Prof. K Watanabe Memorial Article)
• SUBCHRONIC ORAL TOXICITY STUDY WITH CAPTAFOL IN F344 RATS
• CD68^+ Reactive histiocytosis complicating early gastric cancer
• 239 RATS WIDE-SPECTRUM INITATION MUTIPLE ORGAN BIOASSAY MODELS FOR ASSESSING MODIFYING EFFECTS IN NONHEPATOCARCINGENS
• A Prunus mume Extract Stimulated the Proliferation and Differentiation of Osteoblastic MC3T3-E1 Cells
• A Prunus mume Extract Stimulated the Proliferation and Differentiation of Osteoblastic MC3T3-E1 Cells
• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
• Lack of Tumor Promoting Effects of Carrageenan on 1,2-Dimethylhydrazine-induced Colorectal Carcinogenesis in Male F344 Rats
• No Promoting Effect of Ethyl Tertiary-butyl Ether (ETBE)on Rat Urinary Bladder Carcinogenesis Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine

もっと見る 閉じる

スポンサーリンク