SHIMIZU Makiko | Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University

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著作論文

Human blood concentrations of dichlorodiphenyltrichloroethane (DDT) extrapolated from metabolism in rats and humans and physiologically based pharmacokinetic modeling
肝P450等の薬物代謝酵素活性を指標とした日本発新規ヒト型モデル動物"マイクロミニブタ"の非臨床試験における高い将来性
日本人肝におけるフラビン含有モノオキシゲナーゼ3発現の個人差 : 肝転写因子との相関
Complex Mechanism Underlying Transcriptional Control of the Haplotyped Flavin-containing Monooxygenase 3 (FMO3) Gene in Japanese : Different Regulation between Mutations in 5'-Upstream Distal Region and Common Element in Proximal Region
Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
高気圧酸素療法を施した患者の抗がん薬カルボプラチン血漿中濃度測定用HPLC法について
Missense and Nonsense Mutations of the Flavin-containing Monooxygenase 3 Gene in a Japanese Cohort
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
日本人トリメチルアミン尿症の原因となるフラビン含有モノオキシゲナーゼ3遺伝子の新規遺伝子変異
Human Blood Concentrations of Dichlorodiphenyltrichloroethane (DDT) Extrapolated from Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling
Pharmacokinetic Investigation of Increased Efficacy Against Malignant Gliomas of Carboplatin Combined With Hyperbaric Oxygenation
Correlation between the Physicochemical Property of Some Nonsteroidal Anti-inflammatory Drugs and Changes in Adenosine Triphosphate, Glutathione and Hemoglobin in Rat Erythrocytes(Biopharmacy)
Association of the RIP2 Gene with Childhood Atopic Asthma
Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma
Evaluation of Pharmacokinetic parameters of Cibenzoline after Administration of a Single Oral Dose in Healthy Volunteers
Evaluation of Pharmacokinetic Parameters of Cibenzoline after Administration of a Single Oral Dose in Healthy Volunteers
An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway
Population Pharmacokinetic-Pharmacodynamic Modeling of TF-505 Using Extension of Indirect Response Model by Incorporating a Circadian Rhythm in Healthy Volunteers(Biopharmacy)
4'-Hydroxylation of Flurbiprofen by Rat Liver Microsomes in Fasting and Feeding Conditions(Biopharmacy)
Effects of Aspirin and/or Salicylate on Hydrolysis and Glucuronidation of Indomethacin in Rat Erythrocytes and Hepatocytes
Glucuronidation of Propofol and Its Analogs by Human and Rat Liver Microsomes
Testicular Toxicity of Mono-n-Butyl Phthalate and Related Phthalates on Bound Iron in Rat Red Blood Cells
Possible Origin of Rat Testicular Atrophy Induced by Di-n-Butyl Phthalate : Changes in the Activities of Some Enzymes during Rat Testis Perfusion under a Hypoxic Condition and with Mono-n-Butyl Phthalate
A Computer Program for Pharmacokinetics Based on Maximum Likelihood Estimation Using the Gamma Distribution with a Probability Density Function : Comparison with the Normal Distribution
Bonitos with Low Content of Malodorous Trimethylamine as Palliative Care for Self-reported Japanese Trimethylaminuria Subjects

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