New Methods to Evaluate Intestinal Drug Absorption Mediated by Oligopeptide Transporter from In vitro Study using Caco-2 Cells
スポンサーリンク
概要
- 論文の詳細を見る
- 2002-12-16
著者
-
Sezaki H
Faculty Of Pharmaceutical Sciences Setsunan University
-
SEZAKI Hitoshi
Faculty of Pharmaceutical Sciences, Kyoto University
-
Sezaki Hitoshi
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Kyoto University
-
Sezaki Hitoshi
Faculty Of Pharmaceutical Sciences Kyoto University
-
Sezaki Hitoshi
Departments Of Pharmacy Faculty Of Pharmaceutical Sciences Setsunan University
-
Sezaki Hitoshi
Faculty Of Pharmaceutical Sciences Setsunan University
-
Yamashita S
Setsunan Univ. Osaka Jpn
-
Yamashita S
Facuty Of Pharmaceutical Sciences Setsunan University
-
YAMASHITA Shinji
Faculty of Pharmaceutical Sciences, Setsunan University
-
YAMASHITA Shinji
Facuty of Pharmaceutical Sciences, Setsunan University
-
HATTORI Emiko
Faculty of Pharmaceutical Sciences, Setsunan University
-
SHIMADA Aiko
Faculty of Pharmaceutical Sciences, Setsunan University
-
ENDOH Yoriko
Faculty of Pharmaceutical Sciences, Setsunan University
-
YAMAZAKI Yukako
Faculty of Pharmaceutical Sciences, Setsunan University
-
KATAOKA Makoto
Faculty of Pharmaceutical Sciences, Setsunan University
-
SAKANE Toshiyasu
Faculty of Pharmaceutical Sciences, Setsunan University
-
Shimada Aiko
Faculty Of Pharmaceutical Sciences Setsunan University
-
Endoh Yoriko
Faculty Of Pharmaceutical Sciences Setsunan University
-
Hattori Emiko
Faculty Of Pharmaceutical Sciences Setsunan University
-
Yamashita Shinji
Faculty Of Pharmaceutical Sciences Setsunan University
-
Yamazaki Yukako
Faculty Of Pharmaceutical Sciences Setsunan University
-
Yamashita S
Fac. Of Pharmaceutical Sciences Setsunan Univ.
-
Sakane Toshiyasu
School Of Pharmacy Shujitsu University
-
Yamashita S
Departments Of Pharmacy Faculty Of Pharmaceutical Sciences Setsunan University
-
Kataoka Makoto
Faculty Of Pharmaceutical Sciences Setsunan University
関連論文
- Investigation of the Intestinal Permeability and First-Pass Metabolism of Drugs in Cynomolgus Monkeys Using Single-Pass Intestinal Perfusion
- Biliary Excretion of Mitomycin C Dextran Conjugates in Relation of Physicochemical Characteristics of Carrier Dextran
- Effect of Medium-Chain Glycerides on the Membrane Transport of D-Glucose and Sulfanilic Acid in the Intestinal Brush-Border Membrane Vesicles
- EFFECT OF MEDIUM-CHAIN GLYCERIDES (MGK^[○!R]) ON THE INTESTINAL ABSORPTION AND THE HEPATOBILIARY TRANSPORT OF BROMTHYMOL BLUE
- STUDY ON THE ACTION OF PERCUTANEOUS PENETRATION ENHANCERS : EFFECT ON VARIOUS DRUGS WITH DIFFERENT PHYSICOCHEMICAL PROPERTIES
- Analysis of Drug Penetration through Skin Considering Donor Concentration Decrease
- EFFECTS OF MITOMYCIN C, 5-FLUOROURACIL AND CYCLOPHOSPHAMIDE ON DRUG ABSORPTION, ENZYME ACTIVITIES AND MUCOSAL LIPID COMPOSITION OF INTESTINE
- BIOPHARMACEUTICAL STUDIES ON ANTITUMOR DRUG-INDUCED GASTROINTESTINAL DAMAGES
- TRANSPORT CHARACTERISTICS OF p-ACETAMIDOBENZOIC ACID IN BRUSH BORDER MEMBRANE OF RAT SMALL INTESTINE
- EFFECT OF SURFACTANTS ON THE ABSORPTION OF p-AMINOBENZOIC ACID FROM THE RAT INTESTINE
- COMPARATIVE STUDIES ON THE ABSORPTION MECHANISM OF p-AMINOBENZOIC ACID AND p-ACETAMIDOBENZOIC ACID FROM THE RAT INTESTINE
- ABSORPTION AND METABOLISM OF p-AMINOBENZOIC ACID BY RAT SMALL INTESTINE IN SITU
- ABSORPTION AND METABOLISM OF p-AMINOBENZOIC ACID BY RAT INTESTINE IN VITRO
- Cellular Interaction and in Vitro Antitumor Activity of Lipophilic Mitomycin C Prodrugs(Pharmaceutical)
- P-gp誘導 Caco-2 細胞 : P-gp高感度 Assay System の構築
- EVALUATION OF DRUG DISPOSITION IN BRAIN BY MOMENT ANALYSIS (II)
- ELECTROPHYSIOLOGICAL INVERSTIGATIONS ON THE DRUG PERMEATION ACROSS STRATUM CORNEUM (I)
- Effects of Sodium or Glucose Exclusion from the Incubation Medium on Drug Transfer across Rat Jejunal Membrane in Vitro : An Electrophysiological Study(Pharmaceutical)
- EFFECTS OF ABSORPTION PROMOTERS ON THE SELECTIVE PERMEABILITY OF RAT INTESTINAL MEMBRANE TO IONS : ANALYSIS OF PERMEABILITY ENHANCING MECHANISMS BY USING DIFFUSION POTENTIALS
- INVESTIGATIONS OF INFLUX AND ACCUMULATION PROCESSES OF β-LACTAM ANTIBIOTICS AND THEIR ROLE IN THE TRANSMURAL TRANSFER ACROSS RAT JEJUNUM
- FURTHER INVESTIGATIONS ON THE TRANSPORT MECHANISM OF CEPHALEXIN AND AMPICILLIN ACROSS RAT JEJUNUM
- EFFECT OF PHARMACEUTICAL ADJUVANTS ON THE RECTAL PERMEABILITY OF DRUGS
- ELECTROPHYSIOLOGICAL APPROACH TO THE ACTION OF TAURINE ON RAT GASTRIC MUCOSA
- Kinetic Model to Predict the Absorption of Nasally Applied Drugs from in Vitro Transcellular Permeability of Drugs(Biopharmacy)
- Evaluation of the Contribution of the Nasal Cavity and Gastrointestinal Tract to Drug Absorption Following Nasal Application to Rats(Biopharmacy)
- New Methods to Evaluate Intestinal Drug Absorption Mediated by Oligopeptide Transporter from In vitro Study using Caco-2 Cells
- Assessment of Mucosal Immune Response in Genitourinary Tract Using Urine
- Quantitative Evaluation of the Gastrointestinal Absorption of Protein into the Blood and Lymph Circulation
- ANALYSIS OF ACTION MECHANISM OF PERCUTANEOUS PENETRATION ENHANCER BASED ON PHYSIOLOGICAL SKIN DIFFUSION MODEL
- IMMUNOLOGICAL CONTROL OF DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT : EFFECT OF LOCAL ANAPHYLAXIS ON THE INTESTINAL ABSORPTION OF LOW MOLECULAR WEIGHT DRUGS IN THE RAT
- EFFECT OF SYNTHETIC SURFACTANTS ON DRUG ABSORPTION IN THE PRESENCE OF A PHYSIOLOGIC SURFACTANT, SODIUM TAUROCHOLATE, IN RATS
- DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS. II
- DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS.I
- AN ASSESSMENT OF GASTRIC ULCERS IN VIVO : ENHANCEMENT OF URINARY RECOVERY AFTER ORAL ADMINISTRATION OF PHENOLSULFONPHTHALEIN IN RATS
- DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : EFFECT OF ANAPHYLAXIS ON THE ABSORPTION OF SALICYLIC ACID FROM THE RAT SMALL INTESTINE
- ANTIGEN-INDUCED DECREASE OF SALICYLIC ACID ABSORPTION FROM THE SMALL INTESTINE IN ACTIVELY IMMUNIZED RATS
- QUANTITATIVE ANALYSIS OF DRUG DISPOSITION : APPLICATION OF STATISTICAL MOMENT THEORY TO LOCAL PERFUSION SYSTEM
- Tissue Distribution of ^In-Labeled Uricase Conjugated with Charged Dextrans and Polyethylene Glycol
- CONTROL OF IN VIVO FATE OF PROTEIN DRUGS USING CHEMICAL MODIFICATION WITH SUGARS
- INTESTINAL ABSORPTION OF HAPTENS IN RATS IMMUNIZED WITH PROTEIN-HAPTEN CONJUGATE : COMPARISON OF SULFANILIC ACID WITH P-AMINOBENZOIC ACID
- EVALUATION OF ABSORPTIVE BARRIER TO PEPTIDES AND IMPROVEMENT OF MUCOSAL ABSORPTION OF PEPTIDES BY VARIOUS APPROACHES
- Design and Evaluation of Monoclonal Antibody-Antitumor Agent Conjugate
- Cellular Interaction and in Vitro Antitumor Effect of Various Mitomycin C Prodrugs in Mitomycin C-Resistant L1210 Leukemia Cell Lines(Pharmaceutical)
- EFFECT OF TEMPERATURE ON INTESTINAL TRANSFER AND TISSUE UPTAKE OF SULFANILAMIDE AND AMINOPROPYRON IN VITRO
- CELLULAR INTERACTION AND ANTITUMOR ACTIVITY OF MITOMYCIN C PRODRUGS
- URINARY EXCRETION CHARACTERISTICS OF A POLYMERIC PRODRUG OF MITOMYCIN C, MITOMYCIN C-DEXTRAN CONJUGATE
- ENHANCED LYMPHATIC DELIVERY OF MIYOMYCIN C BY POLYMERIC MODIFICATION
- EFFECT OF TAURINE ON THE GASTRIC ABSORPTION OF DRUGS : COMPARATIVE STUDIES WITH SODIUM LAURYL SULFATE
- EFFECT OF TAURINE ON THE GASTROINTESTINAL ABSORPTION OF DRUGS-IONIC REQUIREMENT FOR THE ACTION
- SODIUM ION-DEPENDENCY OF TAURINE-INDUCED ENHANCEMENT OF DRUG ABSORPTION FROM RAT STOMACH IN SITU
- MECHANISM OF THE ABSORPTION OF WATER-SOLUBLE DRUGS FROM THE GASTROINTESTINAL TRACT : ABSORPTION OF β-LACTAM ANTIBIOTICS FROM RAT SMALL INTESTINE
- CARRIER-MEDIATED TRANSPORT SYSTEMS FOR AMINOPENICIL-LINS IN RAT SMALL INTESTINE
- CHARACTERIZATION OF AMINOCEPHALOSPORIN TRANSPORT ACROSS RAT SMALL INTESTINE
- EFFECT OF TAURINE ON DRUG ABSORPTION FROM THE RAT GASTROINTESTINAL TRACT
- EFFECT OF COMPLEXATION WITH DEXTRAN SULFATE ON THE LYMPHATIC DELIVERY OF BLEOMYCIN FOLLOWING INTRASTITIAL ADMINISTRATION
- PHARMACEUTICAL STUDIES ON LIPOSOMES : IMPROVEMENT OF ENTRAPPING EFFICIENCY FOR WATER SOLUBLE DRUGS BY FREEZING METHOD
- Effect of Experimental Acute Renal and Hepatic Failure on Absorption of Tacrolimus in Rat Small Intestine
- 消化管の efflux 機構は,"Phase ゼロ"の elimination!?
- Evaluation of Human P-Glycoprotein (MDR1/ABCB1) ATPase Activity Assay Method by Comparing with in Vitro Transport Measurements : Michaelis-Menten Kinetic Analysis to Estimate the Affinity of P-Glycoprotein to Drugs(Biopharmacy)
- ANTITUMOR ACTIVITY OF LIPOPHILIC PRODRUGS OF MITOMYCIN C ENTRAPPED IN LIPOSOME OR O/W EMULSION
- DEVELOPMENT OF LIPOPHILIC MITOMYCIN C PRODRUGS AND THEIR APPLICATION TO LIPID DISPERSION SYSTEMS
- Application of Dissolution-Permeation/PAMPA System for Prediction of Oral Drug Absorption of Nanoparticle
- In Vitro Dissolution/Permeation System to Predict the Oral Absorption of Poorly Water-Soluble Drugs: Effect of Food and Dose Strength on It
- DIFFERENCES IN EFFECTS ON DRUG ABSORPTION BETWEEN DIHYDROXY AND TRIHYDROXY BILE SALTS
- ENHANCEMENT OF LYMPHATIC TRANSPORT OF 1-(2-TETRAHYDROFURYL)-5-FLUOROURACIL BY WATER-IN-OIL EMULSION
- DEVELOPMENT OF BIFUNCTIONAL DELIVERY SYSTEM FOR SELECTIVE TRANSFER OF DRUG INTO LYMPHATICS VIA ENTERAL ROUTE AND TRANSFER MECHANISM
- ABSORPTION OF 5-FLUOROURACIL FROM VARIOUS REGIONS OF GASTROINTESTINAL TRACT IN RAT. EFFECT OF MIXED MICELLES
- ENHANCED INTESTINAL PERMEABILITY TO MACROMOLECULES. I. EFFECT OF MONOOLEIN-BILE SALTS MIXED MICELLES ON THE SMALL INTESTINAL ABSORPTION OF HEPARIN
- A Theoretical-Empirical Analysis on the Initial Dissolution Rate of Drugs from Polydispersed Particles
- DEGRADATION AND PERMEATION OF PEPTIDE DRUGS IN RAT SMALL INTESTINE AND CACO-2 CELL SYSTEMS
- Effect of Experimental Acute Renal and Hepatic Failure on Absorption of Tacrolimus in Rat Small Intestine
- Preparation of spray-dried microparticles using Gelucire 44/14 and porous calcium silicate or spherical microcrystalline cellulose to enhance transport of water-insoluble pranlukast hemihydrate across Caco-2 monolayers