Enhancement of Localized Heating by Ultrasonically Induced Cavitation in High Intensity Focused Ultrasound Treatment
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概要
- 論文の詳細を見る
There are reports that ultrasonically induced cavitation bubbles locally enhance tissue heating in high intensity focused ultrasound (HIFU) treatment. In this study, a high-intensity burst (named "a triggering pulse") above the cavitation threshold was used to trigger cavitation. Immediately after that, CW ultrasound (named "heating waves"), at an intensity level and duration typical for conventional HIFU ablation was irradiated. Before the ablating sonication, it is necessary to determine the optimum intensity and duration of the triggering pulse. Immediately after a test triggering pulse, low-intensity CW ultrasound (named "a sustaining pulse") was irradiated for a short duration of time, and we detected the cavitation noises (subharmonics and higher harmonics) generated in the focus spot. The relationship between the 1/2 subharmonic signal amplitude and the coagulation volume after the ablating sonication was investigated. The result of this experiment suggests that we can optimize the triggering pulse by detecting the 1/2 subharmonic signal amplitude.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2010-07-25
著者
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Umemura Shin-ichiro
Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan
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Umemura Shin-ichiro
Graduate School of Bioengineering, Tohoku University, 6-6 Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan
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Yoshizawa Shin
Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan
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Takagi Ryo
Graduate school of Engineering, Tohoku University, Sendai 980-8579, Japan
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Yoshizawa Shin
Graduate School of Engineering, Tohoku University, Sendai 980-5879, Japan
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- Enhancement of Localized Heating by Ultrasonically Induced Cavitation in High Intensity Focused Ultrasound Treatment
- Coagulation of Large Regions by Creating Multiple Cavitation Clouds for High Intensity Focused Ultrasound Treatment
- Efficient Generation of Cavitation Bubbles in Gel Phantom by Ultrasound Exposure with Negative-Followed by Positive-Peak-Pressure-Emphasized Waves
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- Optical Phase Contrast Mapping of Highly Focused Ultrasonic Fields
- Analysis of Temperature Rise Induced by High-Intensity Focused Ultrasound in Tissue-Mimicking Gel Considering Cavitation Bubbles
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- Analysis of Temperature Rise Induced by High-Intensity Focused Ultrasound in Tissue-Mimicking Gel Considering Cavitation Bubbles