Modeling of Nanoparticle-Mediated Electric Field Enhancement Inside Biological Cells Exposed to AC Electric Fields
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概要
- 論文の詳細を見る
We present in this article the effect of alternating electric field at kilohertz (kHz) and megahertz (MHz) frequencies on the biological cells in presence and absence of nanoparticles. The induced electric field strength distribution in the region around cell membrane and nucleus envelope display different behavior at kHz and MHz frequencies. The attachment of gold nanoparticles (GNPs), especially gold nanowires around the surface of nucleus induce enhanced electric field strengths. The induced field strengths are dependent on the length of nanowire and create varying field regions when the length of nanowire is increased from 2 to 4 μm. The varying nanowire length increased the induced field strengths inside nucleoplasm and region adjacent to the nucleus in the cytoplasm. We investigated a process of electrostatic disruption of nucleus membrane when the induced electric field strength across the nucleus exceeds its tensile strength.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2009-08-25
著者
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Lee Jae
Department Of Acupuncture & Moxibustion College Of Oriental Medicine
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Kang Sung
Department Of Biological Science Kongju National University
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Choi Jun
Department Of Chemistry Korea Advanced Institute Of Science And Technology
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Kang Sung
Department of Electronic and Electrical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
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Mohamed A.-A.
Department of Electronic and Electrical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
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Kim Gon
Department of Electronic and Electrical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
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Tiwari Pawan
Department of Electronic and Electrical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
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Lee Jae
Department of Electronic and Electrical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea
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