鼻・副鼻腔血管肉腫の一症例

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A 61-year-old male complained of left bloody rhinorrhea and swelling on the left side of the root of the nose for 6 months. Examination of the nose showed an irregular-surfaced and purple mass with a polypoidal configuration.<BR>As frozen-section examination suggested a malignancy, we performed partial maxillectomy.<BR>The histology of the specimen showed invasion by a malignant tumor composed of many irregular, interconnected small and large vascular spaces lined by pleomorphic endothelial cells. Using immunochemical staining, the tumor cells were positive for Factor MU reactive antigen comfirming the diagnosis of an angiosarcoma.<BR>Review of the literature concerning angiosarcoma of the nose and paranasal sinuses revealed 17 previously published cases.<BR>A recent follow-up examination of our case at 55 months revealed no evidence of local tumor recurrence or systemic spread.
耳鼻咽喉科臨床学会の論文