急性リチウム中毒の一症例:神経耳科学的検討

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Tatsuo Funakubo, Tadashi Nakamura, Yo Kimura, Ryoji Kanayama, Makoto Ohki, Ryoichi Sano and Yoshio Koike (Yamagata University)A case of acute lithium intoxication is reported. The patient was a 34-year-old woman, administered lithium at a daily dose of 1000 mg for depression since 1981. On January 21,1990, she took 20 g of lithium to commit suiside and fell into a state of coma. She recovered and was admitted in our Department of Psychiatry.<BR>She showed low consciousness, lingual and mandibular involuntary movements, ataxic gait and dysarthria and was diagnosed as acute lithium intoxication. CT and MRI in dicated no abnormal findings in the brain.<BR>Neuro-otological examination w a s performed on February 19,1990. Spontaneous down-beat nystagmus was shown in the light. A gaze test showed gaze directional nystagmus horizontally and rebound nystagmus. An eye tracking test indicated saccadic pursuit on the horizontal axis and superimposed spontaneous nystagmus on the vertical axis. Slow phase OKN velocity was severely impaired bilaterally. A saccade test showed hypometric saccade, but velocity of which was normal.<BR>These findings suggested that the lesion in t h is case was not only in the cerebellum but also in the brainstem.
耳鼻咽喉科臨床学会の論文