Diffuse Large B-Cell Lymphoma with Mass Lesions of Skull Vault and Ileocecum
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概要
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We report a rare case of non-Hodgkin lymphoma with mass lesions of skull vault and ileocecum. The patient was an 82-year-old Japanese woman who exhibited a painless subcutaneous scalp tumor in the right parietal region associated with no neurological abnormalities. Magnetic resonance imaging of the head demonstrated a mass in the skull vault with iso- to hypointense signals on both T1- and T2-weighted imaging. Biopsy of the mass revealed that the tumor comprised large cells that were immunoreactive for CD20 (L-26) and CD79a. Diffuse large B-cell lymphoma (DLBCL) was therefore diagnosed. Further investigation could not identify any other evidence of systemic lymphoma other than ileocecal lesions. She was treated by irradiation (45 Gy) of the mass on the parietal bone and with rituximab, pirarubicin, cyclophosphamide, and vincristine. The patient achieved complete remission after 3 cycles of systemic chemotherapy. As of 30 months after presentation, no signs of lymphoma have been found. [<I>J Clin Exp Hematop 53(</I><I>3) : 215-219, 2013</I>]
著者
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Moroi Junta
Department Of Neurosurgery Shimonoseki National Hospital
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TAKAHASHI Masatomo
Department of Hematology, St. Marianna University School of Medicine
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Sato Yasukazu
Department Of Internal Medicine Health Insurance Nankai Hospital
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Sakuma Ikuo
Division Of Radiology And Radiation Oncology Department Of Integrated Medicine Akita University Scho
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Nakamura Naoya
Department Of Hematology Niigata University Graduate School Of Medical And Dental Sciences
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Miura Ikuo
Department Of Hematology And Oncology Saint Marianna University School Of Medicine
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Kosugi Shigeki
Department of Internal Medicine, Division of Hematology and Oncology, St. Marianna University School of Medicine
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Kume Masaaki
The Second Department of Internal Medicine, Hiraka General Hospital
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Sato Joji
Department of Internal Medicine, Sato Hospital
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Izumi Keiichi
Department of Surgery, Sato Hospital
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