Effects of the Ankle-brachial Blood Pressure Index and Skin Perfusion Pressure on Mortality in Hemodialysis Patients
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概要
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Objective Clinically, the ankle-brachial blood pressure index (ABI) and skin perfusion pressure (SPP) are used to screen for subclinical peripheral artery disease. However, the association between the SPP and mortality in hemodialysis patients has not been previously reported. We investigated these factors and compared the ABI and SPP in patients receiving hemodialysis. Methods A total of 102 patients receiving maintenance hemodialysis were enrolled in this study. The ABI was determined using an ABI-form (Colin, Japan). The SPP was measured using a SensiLaseTM PAD3000 (Kaneka, Osaka, Japan). Results The mean follow-up period was 3.2±1.4 years. A multivariate Cox analysis identified a low ABI (p=0.019) and a low SPP (p=0.047) as being independent predictors of mortality. A receiver operating characteristic (ROC) analysis of the ABI revealed a cutoff point of 1.1 and an area under the curve (AUC) of 0.79, with a sensitivity of 90% and a specificity of 62%. A ROC analysis of the SPP revealed a cutoff point of 54.0 mmHg and an AUC of 0.71, with a sensitivity of 55% and a specificity of 84%. Conclusion Both low ABI and SPP values were found to be independent risk factors for mortality among hemodialysis patients. The cutoff point for ABI as a predictor of mortality was 1.1, while that for SPP was 54.0 mmHg.
著者
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Otsubo Shigeru
Department Of Electrical Engineering Ishikawa National College Of Tecchnology Tsubata
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Takano Mari
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Miwa Naoko
Department Of Blood Purification Kidney Center Tokyo Women's Medical University
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Kimata Naoki
Department Of Biophysics Graduate School Of Science Kyoto University
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Akiba Takashi
Department Of Blood Purification And Department Of Urology Tokyo Medical And Dental University
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Nitta Kosaku
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Abe Takayuki
Department Of Applied Chemistry Graduate School Of Engineering Tohoku University
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Tsuchiya Ken
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Kimata Naoki
Department of Blood Purification, Kidney Center, Tokyo Women's Medical University, Japan
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Otani Yumi
Department of Clinical Engineering, Tokyo Women's Medical University, Japan
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Okajima Tomoki
Department of Clinical Engineering, Tokyo Women's Medical University, Japan
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Otani Yumi
Department of Clinical Engineering, Tokyo Women's Medical University, Japan
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Okajima Tomoki
Department of Clinical Engineering, Tokyo Women's Medical University, Japan
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Otsubo Shigeru
Department of Blood Purification, Sangenjaya Hospital, Japan
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Tsuchiya Ken
Department of Blood Purification, Kidney Center, Tokyo Women's Medical University, Japan
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Miwa Naoko
Department of Blood Purification, Kidney Center, Tokyo Women's Medical University, Japan
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