Successful Use of Single-Dose Rituximab for the Maintenance of Remission in a Patient with Steroid-Resistant Nephrotic Syndrome
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概要
- 論文の詳細を見る
We present the case of a 23-year-old man with steroid-resistant nephrotic syndrome due to minimal change disease who was treated with rituximab. The patient was resistant to conventional therapy. We therefore treated him with a single dose of rituximab (375 mg/m2). One month after the administration of rituximab, complete remission was achieved. However, six months later, the patient was administered a second dose of rituximab as the peripheral B cell counts began to recover. Thereafter, at present, that is, one year after the first rituximab administration, complete remission has been maintained. We conclude that rituximab may be an effective treatment agent for resistant nephrotic syndrome and the peripheral B cell count may be a useful marker in such patients for preventing disease relapse.
- 社団法人 日本内科学会の論文
著者
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Uchida Keiko
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Itabashi Mitsuyo
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Nitta Kosaku
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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TAKEI Takashi
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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TSUCHIYA Ken
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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Uchida Keiko
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Tsuchiya Ken
東京女子医科大学附属腎臓病総合医療センター 腎臓内科
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Ogawa Tetsuya
Department Of Medicine Kidney Center Tokyo Women's Medical University
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SUGIURA Hidekazu
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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KOJIMA Chiari
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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YOSHIDA Takumi
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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MORIYAMA Takahito
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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ASAMIYA Yukari
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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Moriyama Takahito
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Kurosu Noritomo
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Iwasaki Chihiro
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Tsukada Misao
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Sugiura Hidekazu
Department Of Electrical And Electronic Engineering Tokyo Institute Of Technology
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Kojima Chiari
Department Of Internal Medicine Iv Tokyo Women's Medical University
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Takei Takashi
Department Of Applied Chemistry Graduate School Of Engineering Tokyo Metropolitan University
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Asamiya Yukari
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Ogawa Tetsuya
Department Of Applied Science For Electronics And Materials Kyushu University
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Nitta Kosaku
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Tsuchiya Ken
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Yoshida Takumi
Department Of Medicine Iv Tokyo Women's Medical University
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Itabashi Mitsuyo
Department of Internal Medicine IV, Tokyo Women's Medical University
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Tsukada Misao
Department of Internal Medicine IV, Tokyo Women's Medical University
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Kurosu Noritomo
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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Iwasaki Chihiro
Department of Medicine, Kidney Center, Tokyo Women's Medical University
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