Rituximab Treatment for Adult Patients with Focal Segmental Glomerulosclerosis
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概要
- 論文の詳細を見る
We present two cases with steroid-resistant nephrotic syndrome (SRNS) and two cases with steroid-dependent nephrotic syndrome (SDNS) due to focal segmental glomerulonephritis (FSGS) who were treated with a single dose of rituximab (375 mg/m2). Although the two cases with SRNS showed no response, the two cases with SDNS achieved complete remission. The patients in whom the peripheral B-cell counts subsequently increased after the administration of rituximab demonstrated a relapse. Rituximab may be an effective treatment agent for SDNS with FSGS and the peripheral B-cell count may be a useful marker in such patients for preventing disease relapse.
著者
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Uchida Keiko
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Itabashi Mitsuyo
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Moriyama Takahito
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Iwasaki Chihiro
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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Takei Takashi
Department Of Applied Chemistry Graduate School Of Engineering Tokyo Metropolitan University
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Hattori Motoshi
Department Of Pediatric Nephrology Kidney Center Tokyo Women's Medical University
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Shimizu Ari
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Tsuruta Yuki
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Nitta Kosaku
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Tsuchiya Ken
Department Iv Of Internal Medicine Tokyo Women's Medical University
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Shiohira Shunji
Department Of Medicine Iv Tokyo Women's Medical University
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Ochi Ayami
Department Of Medicine Kidney Center Tokyo Women's Medical University
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Nakayama Kayu
Department Of Medicine Kidney Center Tokyo Women's Medical University
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MOCHIZUKI Toshio
Department II, Hokkaido University Graduate School of Medicine
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Itabashi Mitsuyo
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan
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Kamei Daigo
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan
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Takei Takashi
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan
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Itabashi Mitsuyo
Department of Internal Medicine IV, Tokyo Women's Medical University
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Nakayama Kayu
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan
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Shiohira Shunji
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan
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