Maintenance of the Remission Stage of Crohn's Disease with Adalimumab Therapy during Pregnancy
スポンサーリンク
概要
- 論文の詳細を見る
A 25-year-old pregnant woman complained of abdominal pain and diarrhea. Total colonoscopy provided a diagnosis of Crohn's disease (CD) of the large intestine (Crohn's colitis). Because the patient was allergic to mesalazine, adalimumab (ADA) was used as maintenance therapy during pregnancy, following prednisolone as remission induction therapy. Remission of the patient's CD was maintained with ADA, and the patient delivered a baby girl without any difficulties. Remission of the patient's CD continued to be maintained with the administration of ADA after childbirth. We believe that this is the first report of the use of ADA therapy in a pregnant CD patient in Japan.
著者
-
Joh Takashi
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
-
Ebi Masahide
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
-
Kataoka Hiromi
Department Of Clinical Laboratory Medicine Kochi Medical School
-
Mori Yoshinori
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
-
Mizoshita Tsutomu
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
-
Kamiya Takeshi
Department Of Applied Physics Faculty Of Engineering University Of Tokyo:(present Address) Departmen
-
Tanida Satoshi
Department Of Chemical Engineering And Materials Science Doshisha University
-
Tsukamoto Hironobu
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Sciences
-
Ozeki Keiji
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan
-
Katano Takahito
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan
-
Kataoka Hiromi
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan
関連論文
- Retroperitoneal Fibromatosis in a Cynomolgus Monkey (Macaca fascicularis)
- Impaired gastric motility and its relationship to reflux symptoms in patients with nonerosive gastroesophageal reflux disease
- Roles of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression and β-catenin activation in gastric carcinogenesis in N-methyl-N-nitrosourea-treated K19-C2mE transgenic mice
- Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non-cancerous gastric mucosae
- Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils
- Organ-dependent susceptibility of p53 knockout mice to 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)
- Gastric adenocarcinoma with chief cell differentiation
- Effects of eradication of Helicobacter pylori on gastric carcinogenesis in experimental models
- Helicobacter pylori infection stimulates intestinalization of endocrine cells in glandular stomach of Mongolian gerbils
- Significant Factors on Gastric Carcinogenesis Revealed by Experimental Animal Models
- Gastric and intestinal phenotypes and histogenesis of advanced glandular stomach cancers in carcinogen-treated, Helicobacter pylori-infected Mongolian gerbils
- Colonic and small-intestinal phenotypes in gastric cancers : Relationships with clinicopathological findings
- Susceptibility of Heterozygous and Nullizygous p53 Knockout Mice to Chemical Carcinogens : Tissue Dependence and Role of p53 Gene Mutations
- Coexistence of gastric-and intestinal-type endocrine cells in gastric and intestinal mixed intestinal metaplasia of the human stomach
- Eradication of Helicobacter pylori induces apoptosis and inhibits proliferation of heterotopic proliferative glands in infected Mongolian gerbils
- P6-38 Relationship between hepatic enzyme induction and carcinogenicity in the p53 deficient mice treated with aminophenylnorharman(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- β-Catenin gene alteration in glandular stomach adenocarcinomas in N-methyl-N-nitrosourea-treated and Helicobacter pylori-infected Mongolian gerbils
- Immunohistochemically detectable Cdx2 is present in intestinal phenotypic elements in early gastric cancers of both differentiated and undifferentiated types, with no correlation to non-neoplastic surrounding mucosa
- Detection of Initiating and Promoting Activity of Aminophenylnorharman with a Five-week In Vivo Initiation Assay
- Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation
- β-Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas
- Tissue-dependent susceptibility of p53 knockout mice to chemical-induced carcinogenesis (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Effect of early eradication on Helicobacter pyloirirelated gastric carcinogenesis in Mongolian gerbils
- Gastric Carcinogenesis and Intestinalization Induced by N-methyl-N-nitrosourea in the Senescence-Accelerated Mouse (SAMP3)
- Earlier Helicobacter pylori Infection Increases the Risk for the N-Methyl-N-nitrosourea-induced Stomach Carcinogenesis in Mongolian Gerbils
- Testicular seminoma associated with massive necrosis
- Successful treatment of low-flow priapism associated with phenothiazine therapy
- A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population
- Inhibition of Helicobacter pylori Motility by (+)-Syringaresinol from Unripe Japanese Apricot(Medicinal Chemistry)
- USEFULNESS OF THE MEMORY【○!R】8-WIRE BASKET FORCEPS FOR ENDOSCOPIC EXTRACTION OF COMMON BILE DUCT STONES AFTER ENDOSCOPIC SPHINCTEROTOMY
- CLINICAL EVALUATION OF THE HABER RAMP^ CATHETER FOR ENDOSCOPIC BILATERAL METAL STENT PLACEMENT IN PATIENTS WITH MALIGNANT HILAR STRICTURES
- Combination chemotherapy with cisplatin and gemcitabine in malignant peritoneal mesothelioma
- Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil
- Establishment and characterization of a human colonic mucinous carcinoma cell line with predominant goblet-cell differentiation from liver metastasis
- Collaborative work on evaluation of ovarian toxicity : 8) Two- or four-week repeated-dose studies and fertility study of Anastrozole in female rats
- Ganglioneuroma in the Urinary Bladder of a Dog
- Effect of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis C virus infection
- Impaired Gastric Motility in Patients with Functional Dyspepsia
- Alteration of the responses of gastric smooth muscle to endothelin in streptozotocin-induced diabetic rats
- Improvement of gastric motility by hemodialysis in patients with chronic renal failure
- Impaired gastric motility and its relationship to gastrointestinal symptoms in patients with chronic renal failure
- Effects of endothelin-1 on the membrane potential and slow waves in circular smooth muscle of rat gastric antrum
- Proliferation marker MIB-1 correlates well with proliferative activity evaluated by BrdU in breast cancer : An immunohistochemical study including correlation with PCNA, p53, c-erbB-2 and estrogen receptor status
- Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats
- Accidental exposure to HCV antibody-positive blood in hospital and pre-emptive one-shot interferon alpha-2b treatment
- Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs
- CLINICAL EVALUATION OF METALLIC STENTING FOR MALIGNANT DUODENAL OBSTRUCTION USING COVERED SELF-EXPANDABLE METALLIC STENT
- Clinical Differences Between Primary Sclerosing Cholangitis and Sclerosing Cholangitis With Autoimmune Pancreatitis
- AUTOIMMUNE PANCREATITIS ASSOCIATED WITH BILIARY STRICTURE, IMMUNE THROMBOCYTOPENIC PURPURA AND LUNG FIBROSIS
- Ischemia-reperfusion injury in the stomach : role of complement
- Osteosarcomas in the Lungs of an ICR Mouse
- Hepatozoon ursi n. sp. (Apicomplexa : Hepatozoidae) in Japanese black bear (Ursus thibetanus japonicus)
- Evaluation of Cell Proliferation in Canine Tumors by the Bromodeoxyuridine Labeling Method, Immunostaining of Ki-67 Antigen and Proliferating Cell Nuclear Antigen
- Immunohistochemical Demonstration of S-phase Cells in Canine and Feline Spontaneous Tumors by Anti-bromodeoxyuridine Monoclonal Antibody
- Solitary bone metastasis as the first clinical manifestation in a patient with small bowel adenocarcinoma
- Immunohistochemical Staining Methods for Connexin32 on Formalin-Fixed Paraffin-Embedded Sections
- Pulmonary Histiocytic Sarcoma in Two Aged Dogs of a Beagle Colony
- Autoimmune Pancreatitis Associated with Various Extrapancreatic Lesions during a Long-term Clinical Course Successfully Treated with Azathioprine and Corticosteroid Maintenance Therapy
- Properties of Inhibitory Junctional Transmission in Smooth Muscle of the Guinea Pig Lower Esophageal Sphincter
- Bronchioloalveolar Carcinoma in an Aged Beagle Dog
- GASTRIC SCHWANNOMA WITH ADJACENT EXTERNAL PROGRESSION HARBORED ABERRANT NF2 GENE
- Bone morphogenetic protein 2 induced differentiation toward superficial epithelial cells in the gastric mucosa
- Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population : a randomized, double-blind, placebo-controlled trial
- Severe Ascites with Hypothyroidism and Elevated CA125 Concentration : A Case Report
- Gastric carcinogenesis by N-Methyl-N-Nitrosourea is enhanced in db/db diabetic mice
- Endoscopic transpapillary intraductal ultrasonography and biopsy in the diagnosis of IgG4-related sclerosing cholangitis
- Systemic extrapancreatic lesions associated with autoimmune pancreatitis
- PEUTZ-JEGHERS SYNDROME ASSOCIATED WITH RENAL AND GASTRIC CANCER THAT DEMONSTRATED AN STK11 MISSENSE MUTATION
- Susceptibility to Killer T Cells of Gastric Cancer Cells Enhanced by Mitomycin-C Involves Induction of ATBF1 and Activation of p21 (Waf1/Cip1) Promoter
- EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments
- A Catalogue of genes in Mouse Embryonal Carcinoma F9 Cells Identified with Exprssed Sequnce Tags^1
- Relationship Between Doppler Transmitral Flow Velocity Pattern and Plasma Atrial and Brain Natriuretic Peptide Concentrations in Anuric Patients on Maintenance Hemodialysis
- Liver Atrophy and Portal Stenosis in Two Cases of Sclerosing Cholangitis Associated with Autoimmune Pancreatitis
- Bronchioloalveolar Carcinoma in an Aged Beagle Dog
- Cretaceous radiolarian fossils from the Ryujin Formation of the Shimanto Belt in the Kawabe area, Wakayama Prefecture, southwest Japan
- Mixed Type of Malignant Mesothelioma in an Aged Male ICR Mouse
- Heterotopic Pancreas in the Stomach which Caused Obstructive Stenosis in the Duodenum
- AN ENDOCRINE CELL CARCINOMA WITH GASTRIC-AND-INTESTINAL MIXED PHENOTYPE ADENOCARCINOMA COMPONENT IN THE STOMACH
- Pyeloplasty in Hydronephrosis: Examination of Surgical Results from a Morphologic Point of View
- CARDIOVASCULAR TOLERANCE AND AUTONOMIC NERVOUS RESPONSES IN UNSEDATED UPPER GASTROINTESTINAL SMALL-CALIBER ENDOSCOPY : A COMPARISON BETWEEN TRANSNASAL AND PERORAL PROCEDURES WITH NEWLY DEVELOPED MOUTHPIECE
- A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan
- Small bile duct involvement in IgG4-related sclerosing cholangitis : liver biopsy and cholangiography correlation
- Low-dose carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in rats : Evidence for the existence of no-effect levels and a mechanism involving p21^
- Clinical characteristics of inflammatory bowel disease associated with primary sclerosing cholangitis
- Diagnostic procedures for IgG4-related sclerosing cholangitis
- A Rare Case of Infectious Colitis with Ulcers in the Cecum Caused by Mycobacterium Gordonae
- Diagnostic criteria for IgG4-related sclerosing cholangitis based on cholangiographic classification
- The effect of omeprazole on gastric myoelectrical activity and emptying
- Proliferative Potential of a Spinal Nephroblastoma in a Young Dog
- Combination Therapy with Adalimumab Plus Intensive Granulocyte and Monocyte Adsorptive Apheresis Induced Clinical Remission in a Crohn's Disease Patient with the Loss of Response to Scheduled Adalimumab Maintenance Therapy: A Case Report
- A Patient with Gastric Adenosquamous Carcinoma with Intraperitoneal Free Cancer Cells who Remained Recurrence-free with Postoperative S-1 Chemotherapy
- A Case of Autoimmune Pancreatitis Showing Narrowing of the Main Pancreatic Duct after Cessation of Steroid Therapy in the Clinical Course
- Maintenance of the Remission Stage of Crohn's Disease with Adalimumab Therapy during Pregnancy
- Is Proton Pump Inhibitor Therapy for Reflux Esophagitis Sufficient?: A Large Real-world Survey of Japanese Patients
- Alendronate-Induced Esophagitis: Possible Pathogenic Role of Hypersensitivity to Alendronate
- Effects of Pitavastatin on Remnant-Like Lipoprotein Particle Cholesterol in Patients with Dyslipidemia : A Randomized Controlled Trial
- A Case of IgG4-related Sclerosing Cholangitis Overlapped with Primary Biliary Cirrhosis
- Recommendation of lamivudine-to-entecavir switching treatment in chronic hepatitis B responders : Randomized controlled trial
- Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats
- Analysis of VH gene rearrangement and somatic hypermutation in type 1 autoimmune pancreatitis