Combination Therapy with Adalimumab Plus Intensive Granulocyte and Monocyte Adsorptive Apheresis Induced Clinical Remission in a Crohn's Disease Patient with the Loss of Response to Scheduled Adalimumab Maintenance Therapy: A Case Report
スポンサーリンク
概要
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A 21-year-old Caucasian man with a diagnosis of Crohn's disease (CD) at the age of 14 was admitted to our hospital due to CD flare-up while under scheduled adalimumab (ADA) maintenance therapy. His symptoms remained virtually unchanged following high dose corticosteroid therapy. Seven days later, combination therapy with ADA plus intensive granulocyte/monocyte adsorptive apheresis (GMA) was initiated, which induced clinical remission. Therefore, combination therapy with ADA plus intensive GMA appears to be an effective therapeutic option for patients with severe CD while under scheduled ADA maintenance therapy.
著者
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Shimura Takaya
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
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Joh Takashi
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
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Kataoka Hiromi
Department Of Clinical Laboratory Medicine Kochi Medical School
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Hirata Yoshikazu
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
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Mizoshita Tsutomu
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
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Kamiya Takeshi
Department Of Applied Physics Faculty Of Engineering University Of Tokyo:(present Address) Departmen
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Tanida Satoshi
Department Of Chemical Engineering And Materials Science Doshisha University
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Murakami Kenji
Department Of Biosciences School Of Science And Engineering Teikyo University
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Tsukamoto Hironobu
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Sciences
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Ozeki Keiji
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan
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Kataoka Hiromi
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan
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Mizushima Takashi
Gifu Prefectural Tajimi Hospital, Japan
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