Effect of Different Kinds of Exercise on Serum Uric Acid

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The study was investigated effects of different kinds of exercise on serum uric acid as the basic research data for preventing athletes and non-athletes from exercised-induced hyperuricemia and carring out exercise treatment for hyperuricemia. The results were summarized as follows: 1) Changes in serum uric acid on different kinds of exercise: On an exhaustive exercise on a bicycle ergometer for 5-10 min, serum uric acid was gradually increased, and reached a peak at 2 hrs after exercise. And then it was gradually decreased until 24 hrs after exercise, but was significantly 9.9% higher at 24 hrs after exercise than before exercise (p<0.001). On a 12 min-run, serum uric acid reached a peak immediatly after ex ercise, and then kept the same level until 2 hrs after exercise. On a 2 hrs running on a treadmill, serum uric acid showed a linear increase, and reached a peak at 45 min during exercise. And then it was the same level until 90 min after exercise. 2) Comparison of the degree of increase in serum uric acid on different kinds of exercise: The degree of increase in serum uric acid against before exercise was the largest (+87.9%, p<0.001) on an exhaustive exercise on a bicycle ergometer in untrained subjects, and was with a range of +9.0 to +34.2% on a 12-min -run, a 2 hrs running on a treadmill and so on. 3) Relationship between exercise in t e nsity and increase inserum uric acid when the amount of exercise was the same: The increase in serum uric acid after exercise was proportional to exercise intensity on 60%, 80%, and 100% V02 max. But serum uric acid was almost unchanged after 40% V02 max exercise, and tended to be decreased after 30% V02 max exercise. 4) The ratio of appearence of exercise-induced hyperuricophenomenon (phenomenon of a temporary high level of serum uric acid over 7 mg/dl after severe exercise): The ratio of appearence of exercise-induced hyperurico-phenomenon was 38.1% (75 out of 197 untrained subjects) at 5,000m run, and 53.3% (16 out of 30 trained subjects) at 12-min-run. 5) Effects of training on the degree of increase in serum uric acid after exercise: After training of walking and jogging for 4 months, the mean distance of 12-min-run was increased (2,444m→2,611m), but the degree of increase in serum uric acid after 12mm-run was decreased (+18.3%→+9.1%) in contrast to before training.

Effect of Different Kinds of Exercise on Serum Uric Acid

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