Long-term Outcome after Multidisciplinary Approach for Leptomeningeal Carcinomatosis in a Non-small Cell Lung Cancer Patient with Poor Performance Status
スポンサーリンク
概要
- 論文の詳細を見る
The present study describes a case of a 60-year-old Japanese man who was histologically diagnosed with lung adenocarcinoma harboring L858R mutation of epidermal growth factor receptor. He was successfully treated with gefitinib, but eventually developed leptomeningeal carcinomatosis. He underwent ventriculoperitoneal shunting for hydrocephalus and received erlotinib in place of gefitinib with concurrent whole brain radiotherapy; this resulted in dramatic improvement in his symptoms and performance status from four to one and he survived for as long as 13.6 months after the initiation of erlotinib therapy. This multidisciplinary approach may be particularly useful in terms of increasing survival and improving quality of life.
- 社団法人 日本内科学会の論文
著者
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Funada Yasuhiro
Division Of Respiratory Medicine Department Of Internal Medicine Kobe University Graduate School Of
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Kotani Yoshikazu
Division Of Respiratory Medicine Department Of Internal Medicine Kobe University Graduate School Of
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Kobayashi Kazuyuki
Division Of Respiratory Medicine Department Of Internal Medicine Kobe University Graduate School Of
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Kondoh Takeshi
Department Of Community Dentistry Matsumoto Dental College
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Nishimura Yoshihiro
Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University
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Nagano Tatsuya
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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Kotani Yoshikazu
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Hatakeyama Yukihisa
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Hori Suya
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Kasai Daisuke
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Nishimura Hideki
Divison of Radiation Oncology, Department of Radiology, Kobe University Graduate School of Medicine, Japan
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Funada Yasuhiro
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Nagano Tatsuya
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan
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Kondoh Takeshi
Department of Neurosurgery, Kobe University Graduate School of Medicine, Japan
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