Complete remission of hyperprolactinemia after laparoscopic myomectomy -A case report-

概要

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Prolactin(PRL) affects more physiological process than all other pituitary hormones combined. Normal myometrium and uterine fibroids secrete PRL, but the function of myometial PRL is unknown. We report a case of complete remission of hyperprolactinemia after laparoscopic myomectomy. The patient was 37 years-of-age, gravid 0, para 0. She was referred to our hospital elsewhere because of a diagnosis with hyperprolactinemia and uterine myoma. At the age of 35, she had been diagnosed with secondary amenorrhea and hyperprolactinemia. Brain MRI and CT scans failed to detect any morphological abnormality. She had been taking cabergoline followed by terguride for nearly two years, but her hyperprolactinemia failed to respond to the deopamine agonists despite a gradual increase of their dosages. However, the hyperprolactinemia unexpectedly regressed completely after the patient underwent laparoscopic myomectomy. The rapid normalization of this patient's high-dose dopamine agonist resistant hyperprolactinemia after myomectomy clearly demonstrates that these conditions were due to her uterine myoma.