Synthesis of 7-Substituted 6,7-Dihydro-5H-pyrrolo(3,4-b)pyridin-5-ones. Reaction of 7-Hydroxy Derivatives with Nucleophiles.

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概要

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• Various 7-substituted 6,7-dihydro-5<I>H</I>-pyrrolo[3,4-<I>b</I>]pyridin-5-ones are synthesized by the reaction of the corresponding 7-hydroxy derivatives with nucleophiles involving active methylene compounds, aromatics, alcohols, <I>p</I>-toluenethiol, benzenesulfinic acid, triethyl phosphite, ammonia, and amines under acidic or basic conditions. Some synthetic applications of the products obtained are demonstrated to give a 7-methylene derivative and fused tricyclic derivatives.

• 公益社団法人 日本化学会の論文

著者

• Sato Ryu

  Department Of Applied Chemistry And Molecular Science Faculty Of Engineering Iwate University

• Ishizaki Takeshi

  Department Of Fundamental Nursing Fukui Medical University

• Saito Minoru

  Department Of Agricultural Engineering Faculty Of Agriculture Kagawa University

• Goto Takehiko

  Department of Resource Chemistry, Faculty of Engineering, Iwate University

• Ishizaki Takeshi

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

• Utsunomiya Shin

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

• Aiba Hiroshi

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

• Hayasaka Hirotaka

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

• Endo Mikihiro

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

• Watanabe Reo

  Department of Resource Chemistry, Faculty of Engineering, University of Iwate

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