The Reaction of Nitriles with Phosgene. VII. Synthesis of α,β-Unsaturated Isocyanates
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概要
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The reaction of nitriles with phosgene in the presence of hydrogen chloride was carried out for synthesizing α,β-unsaturated isocyanates. 3-Chloropropionitrile, 2,3-dichloropropionitrile, isobutyronirtile, and 2-chloromethylpropionitrile gave the corresponding α-chloro-α,β-unsaturated isocyanates in moderate yields (27–50%). Propionitrile, <I>n</I>-butyronitrile, and 3-phenylpropionitrile gave the corresponding pyrimidines as the major product. 3-Phenylpropionitrile, however, gave the isocyanate as the major product when the amount of benzene as a solvent increased. Reaction pathways to isocyanates and pyrimidines were discussed.
- 公益社団法人 日本化学会の論文
著者
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OKAHARA Mitsuo
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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Yanagida Shozo
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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Komori Saburo
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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Fujita Tetsuo
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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Ohoka Masataka
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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Sugahara Kenji
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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