破裂脳動脈瘤の脳虚血に対する Fluosol-DA 20 および Dopamine の有用性に関する検討:-特に局所脳循環面より-

概要

論文の詳細を見る
Nowadays, cerebral ischemia due to angiospasm was treated with several drugs. However, we were not able to find most available treatment, yet.<BR>We used Fluosol DA-20 and dopamine for treatment of ischemic symptoms perhaps due to angiospasm and got following data from neurological examination and rCBF studies, repeated CT scans. Clinical symptoms were remarkably improved, especially most effective on consciousness level during Fluosol DA-20 infusion and dopamine with Fluosol DA-20. A case using Fluosol DA-20 revealed improvement of clinical symptom without increase of cerebral blood flow. This mechanism is probably related to ability of oxygen content of Fluosol.<BR>Surrounding area of cerebral ischemia showed cerebral blood flow increase with Fluosol DA-20 and/or dopamine infusion, however, ischemic region due to vasospasm did not reveal any increase of blood flow
The Japanese Society on Surgery for Cerebral Strokeの論文