焦点性てんかんの局所脳循環に関する研究 : 特に焦点部位の自己調整能を中心として

概要

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rCBF measurements were performed in six patients with focal cortical epilepsy by using the 254 Detector Dynamic Gamma Camera with ^<133>Xe clearance technique and rCBF patterns were displayed on colour TV with digital memories for 16 colours and graphs. After injections of Angiotensin rCBF measurements were also performed. Those rCBF changes between ictal or interictal phases and injection of Angiotensin were compared to each other. The results obtained were as follows: 1. Six patients showed focal hyperaemia in the same regions of epileptogenic foci. Especially the patient with status hemi-epilepticus showed 2-10 times increased rCBF compared with nonfocal areas. 2. The patients with cryptogenic etiology and glioblastoma showed marked disturbances of autoregulation in focal hyperaemic areas and also mild disturbances in non-focal areas. 3. The patients with preoperative and postoperative meningioma showed no disturbances of autoregulation in both focal and non-focal areas.
日本脳神経外科学会の論文