Studies on the Constituents of Lagochilus leiacanthus (Labiatae)
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概要
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Two flavanones, 5,2′,6′-trihydroxy-7,8-dimethoxyflavanone (1), 5,2′,6′-trihydroxy-6,7,8-trimethoxyflavanone (2) and their 2′-O-β-D-glucosides (3, 4), and a neoclerodane-type diterpene, 15-demethoxyscupolin I (5), together with twenty-eight known compounds were isolated from the extracts of Lagochilus leiacanthus. The structures of the new compounds were determined by spectroscopic means. The two new flavanones and some known flavonoids showed the inhibitory activity on the release of β-hexosaminidase from RBL-2H3 cells.
著者
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Makino Mitsuko
Department Of Chemistry College Of Humanities And Sciences Nihon University
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Ogawa Shoujiro
Department Of Chemistry College Of Humanities & Sciences Nihon University
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Suzuki Hideya
Department Of Agricultural Chemistry Faculty Of Agriculture Ibaraki University
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Iida Takashi
Departmenr Of Neuropathology Neurological Institute Graduate School Of Medical Sciences Kyushu Unive
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Furukawa Megumi
School Of Pharmacy Nihon Univ.
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Fujimoto Yasuo
Department of General Education, College of Humanities and Sciences, Nihon University
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Suzuki Hideya
Department of Chemistry, College of Humanities and Sciences, Nihon University
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