初発症状発現後11年を経過し急性肺水腫で死亡した大動脈炎症候群の1剖検例

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A 46-year-old woman was admitted to our hospital because of dyspnoea, cyanosis of the lips and excessive foaming sputa. She died of respiratory insufficiency 40 minutes after admission. Autopsy examination revealed that the rumen of the upper aortic arch and its main branch artery were enlarged, while the lower breast aorta was silightly constricted, and there was severe edema of the lungs. Histopathological findings showed increased connective tissues in the externa of the aorta and hypertrophy in the intima. The heart was enlarged to 350g in weight, and concentric hypertrophy and breakdown of cardial myofibrils were prominent in a microsection of the left ventricle. This patient had symptoms suggesting aortitis syndrome at the age of 35, and 11 years later, died of acute pulmonary edema.
学校法人昭和大学・昭和医学会の論文