Sulpyrinum(Metilon)による心停止の一症例

概要

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A male, aged 68, was admitted for transvesical prostatectomy with a diagnosis of prostatic hypertrophy. He had a high fever of unknown cause on 24th day after the operation and one cc of 50 w/v % sulpyrinum (Metilon), which had caused untoward reaction in 'this patient about 21 days ago, was administered intramuscularly. Within a few minutes after injection, anaphylactic shock developed and progressed to cardiac arrest. Artificial ventilation and closed-chest cardiac massage were started immediately, and spontaneous heart beat reappeared after 20 minutes. Because of respiratory failure, a tracheostomy was performed and his respiration was controlled or assisted with respirator for 7 days. He did not regain consciousness, and eventually expired on 197th day after cardiac arrest.<BR>Cause of anaphylactic shock and its treatment, emergency resuscitation, prognosis of cardiac arrest, long-term artificial ventilation were discussed in detail.
学校法人昭和大学・昭和医学会の論文