耳鼻咽喉科患者のツベルクリン(PPD)皮内反応 (三吉康郎教授開講20周年記念論文集)

概要

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Immunological reactivity by means of the PPD skin reaction were studied in 1, 235 patients, who were admitted to the Department of Otolaryngology, Mie University Hospital, from 1976 to 1980.The overall rate of positive reaction was 42.1%. The rate was significantly different between males and females. Of the 980 patients with benign disease the rate was 40.5%, while of the 225 patients with malignant tumor the rate was 48.2%. In patients with malignant tumor, response to the PPD was positive in 53.3% at stage I, 68.2% at stage II, 41.3% at stage III and 42.6% at stage IV. There was a statistically significant difference in the rate of positive skin reaction among stage I, II and III, IV. The patients with positive skin reaction to the PPD at the time of admission were found to have a more favourable prognosis in comparison with those who were negative to the PPD.These findings suggest that the skin test reactivity to the PPD may be of use in patient management as one of the parameters of the host immune response.
耳鼻咽喉科臨床学会の論文