鼻アレルギ-に対するヒスタグロビン・ネブライザ-療法の臨床的検討

概要

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To evaluate the clinical effect and safety of Histaglobin nebulizer therapy, 18 patients suffering from house-dust nasal allergy were treated with this drug. These subjects were divided into two groups with nine subjects in each group. The patients of group A were given 1/4 vials three times per week for a total of 24 times. The subjects of group B were treated with 1/2 vials twice per week for a total of 12 times. All subjects in both groups received a total dosage of 6 vials. The effects on the subjects of the two groups were compared. The results obtained were as follows:1) The effective rate was 78% for group A and 56% for group B.2) The rate of improvement in nasal congestion was 89% for group A and 67% for group B. The decrease in rhinorrhea was 89% for group A and 56% for group B. The decrease in the number of sneezing attacks was 67% for group A and 44% for group B.3) From the laboratory findings, it was found that the serum level of IgE antibody fell after the treatment in three subjects. The histaminopexic power rose after the treatment in ten subjects.4) There was no side effect observed in any subject.Histaglobin nebulizer therapy was considered to be very effective and safe for the treatment of house-dust nasal allergy.
耳鼻咽喉科臨床学会の論文