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A clinical study was performed of 55 patients with laryngeal cancer treated in the Department of Otorhinolaryngology, Yamaguchi University, from 1978 through 1982.1. The male to female ratio was about 13:1.2. There were 31 tumors (56%) of glottic, 18 (33%) of supraglottic and 3 (5.5%)of subglottic origin.3. Histopathologically, 93 percent were squamous cell carcinoma.4. More stage IV cancers were noted in the supraglottic than in the glottic group. (glottic 10%, supraglottic 56%) Metastases to the cervical lymph nodes were present in 6.5 percent of the glottic and in 55.6 percent of the supraglottic cases.5. Fifty-three percent (23 cases) were treated with combinations of irradiation, operation and anticancer drugs.6. The 5-year survival rate was 84.7 percent, glottic type 84.8 percent and supraglottic 80.4 percent.These results led us to establish the following guidelines for the treatment of cancers of the larynx:For patients with T1 or T2 lesions of glottic origin, radiotherapy is recommended first, and if it is not effective, partial laryngectomy as a salvage operation is recommended.For patients with T3 or T4 glottic lesions, total laryngectomy after radiotherapy is recommended.For patients with supraglottic cancer one should determine the level of treatment after examining the cervical lymph nodes for metastases.
耳鼻咽喉科臨床学会の論文