Antimicrobial Activity of Chitosan with Different Degrees of Acetylation and Molecular Weights
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概要
- 論文の詳細を見る
The antimicrobial activity of chitosan with different molecular weights (MWs) and different degrees of acetylation (DA) was examined to clarify how the activity depends upon the molecular structures. We determined minimum growth inhibitory concentrations (MICs) of various types of chitosan in L broth or its modified medium against bacteria and yeasts. The MICs against Gram-positive bacteria were relatively low for chitosan preparations with higher MWs and that against Gram-negative bacteria were at their minimum at around a MW of 11, 000 to 30, 000. An increase in the DA of the amino group in the chitosan molecule caused less activity. The antimicrobial activity varied with the genus as well as species of bacteria and yeasts. For application of chitosan as a preservative to food, pharmaceuticals, and other materials, the data obtained here on the characteristics and antimicrobial spectrum may be useful.
- 日本防菌防黴学会の論文
- 2003-03-20
著者
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NAKAMURA ICHIRO
Chukyo Community College
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Akiyama Takahiro
Tottori R&d Center Daishin Chemical Co. Ltd.
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Shigemasa Yoshihiro
Department Of Industrial Chemistry Faculty Of Engineering Tottori University
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Nakamura I
Tribiox Laboratories Ltd.
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OMURA YOSHIHIKO
TriBioX Laboratories, Ltd.
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Omura Yoshihiko
Omura Toryo Co. Ltd.
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Omura Yoshihiko
Tribiox Laboratories Ltd.
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Shigemoto Mayumi
Omura Toryo Co. Ltd.
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Tsuchido Tetsuaki
Department Of Biotechnology Faculty Of Engineering And High Technology Research Center Kansai Univer
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Saimoto Hiroyuki
Department Of Chemistry And Biotechnology Graduate School Of Engineering Tottori University
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AKIYAMA TAKAHIRO
Tottori R & D Center, Daishin Chemical Co., Ltd.
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