New methods for the synthesis of 3(2H)-furanones and 2(5H)-furanones.
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概要
- 論文の詳細を見る
New procedures for the synthesis of 3(2<I>H</I>)-furanones and 4-alkoxy-2(5<I>H</I>)-furanones are reported. Reaction of ketones with the lithium salt of propynal diethyl acetal, followed by treatment of the resulting 4-hydroxy-2-alkynal diethyl acetals with sulfuric acid–methanol, gave 2,2-disubstituted 3(2<I>H</I>)-furanones. The action of a polymer reagent Hg/Nafion-H upon 4–hydroxy-2-alkynones produced 2,2,5-trisubstituted 3(2<I>H</I>)-furanones. Reaction of 1,1,1-triethoxy-2-alkyn-4-ols (<B>4</B>) with trifluoroacetic acid and mercury(II) acetate provided 5-ethoxy-2,2-disubstituted 3(2<I>H</I>)-furanones. In contrast, the adducts <B>4</B> were converted into 4-alkoxy-5,5-disubstituted 2(5<I>H</I>)-furanones upon reaction with Hg/Nafion-H.
- 公益社団法人 日本化学会の論文
著者
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Hiyama Tamejiro
Department Of Marerial Chemistry Graduate School Of Engineering Kyoto University
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Shinoda Masaki
Department Of Neurosurgery Tokai University School Of Medicine
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Oshima Koichiro
Department Of Industrial Chemistry Faculty Of Engineering Kyoto University
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Saimoto Hiroyuki
Department Of Chemistry And Biotechnology Graduate School Of Engineering Tottori University
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Nozaki Hitosi
Department of Industrial Chemistry, Faculty of Engineering Kyoto University
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Matsubara Seijiro
Department of Industrial Chemistry, Kyoto University
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Matsubara Seijiro
Department of Industrial Chemistry, Faculty of Engineering Kyoto University
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Oshima Koichiro
Department of Chemistry, Massachusetts Institute of Technology
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Hiyama Tamejiro
Department of Industrial Chemistry, Kyoto University
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Hiyama Tamejiro
Department of Industrial Chemistry, Faculty of Engineering, Kyoto University
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Shinoda Masaki
Department of Industrial Chemistry, Kyoto University
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