Alkylation of bromocyclopropanes and bromoarenes by means of dibutylcopperlithium and alkyl halides.
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概要
- 論文の詳細を見る
Treatment of bromocyclopropanes with excess dibutylcopperlithium in tetrahydrofuran at −48 °C gives the respective organocopper intermediates which upon quenching with excess alkyl halides afford alkylated cyclo-propanes with retention of the configuration. This process is applied to the synthesis of methyl cascarillate. Bromoarenes are also reduced with dibutylcopperlithium and allylarenes are prepared therefrom.
- 公益社団法人 日本化学会の論文
著者
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YAMAMOTO Hajime
Department of Applied Physics and Chemistry, The University of Electro-Communications
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Hiyama Tamejiro
Department Of Marerial Chemistry Graduate School Of Engineering Kyoto University
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Nozaki Hitosi
Department of Industrial Chemistry, Faculty of Engineering Kyoto University
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Nishio Koji
Department of Industrial Chemistry, Kyoto University
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Nishio Koji
Department of Anatomy, Nagoya University School of Medicine
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Kitatani Katuzi
Department of Industrial Chemistry, Kyoto University
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