結核の集団発生--同一職場における7症例の発症状況の観察

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A 38-year-old male with sputum positive for tubercle bacilli who had a history of administrationof anti-tuberculous drugs was found in a furniture company in Okayama city. The routine chest X-ray examinations in twenty-eight employees of the company has been done twice a year after thediscovery of this patient. As the result of the study, the other four male and two female patients whoseages ranged from twenty to thirty-two, were found during the follow-up of twenty-nine months. Fiveout of six patients were discovered by the routine X-ray examinations without symptoms, and onlyone was symptomatic. In the family of the index case, his wife and mother developed pulmonarytuberculosis, and the PPD skin tests of his children were found to be strongly positive. Studies on the relationship between the index case and the other six cases suggest the following; 1) The tuberculosis epidemic may occur even in adult, when they have close contact with apatient who discharges a large amount of tubercle bacilli. 2) The detection of positive conversion of the PPD skin test is very useful to investigate the tuberculosis epidemic, however its use is limited due to high coverage of BCG vaccination in children andyoung adult. 3) The identification of the drug resistant pattern of tubercle bacilli is also important in studying the epidemic, but in the present epidemic only two out of seven cases were positive on culture. Thepattern in two strains was similar with each other. 4) The time interval from the contact with the index case to the onset of tuberculosis is distributed in a long period of term in contrast to the other infections diseases epidemic.
一般社団法人日本結核病学会の論文

結核の集団発生--同一職場における7症例の発症状況の観察

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