Effect of individual amino acids on plasma cholesterol level in rats fed a high cholesterol diet.

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概要

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• The effect of individual amino acids added to a cholesterol containing casein diet on the plasma cholesterol level of rats was systematically investigated with objective of confirming the possibility that specific amino acids are responsible for the regulation of plasma cholesterol level by dietary proteins. Half the amino acids tested were effective to some degree in influencing the plasma cholesterol level when amino acids were added singly to the diet at a 5% level. However, only sulfur containing amino acids had significant effects when added to the diet at a 1% level; Met enhanced and Cys reduced the plasma cholesterol level. In addition, the results of an experiment with amino acid mixture diets with different Met, Cys, and/or Gly contents indicated the importance of sulfur amino acids and also of Gly in plasma cholesterol regulation. The results obtained here support the notion that the plasma cholesterol level of rats can be influenced by specific amino acids or amino acid compositions of dietary proteins, at least under the experimental conditions used.

• 財団法人 学会誌刊行センターの論文

著者

• 村松 敬一郎

  Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture

• 杉山 公男

  Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University

• 水野 雅之

  Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University

関連論文

• THE RELATIONSHIP BETWEEN WEIGHT GAIN AND FREE AMINO ACID CONCENTRATION OF PLASMA AND LIVER IN RATS FED A DIET SUPPLEMENTED WITH VARIOUS AMOUNTS OF LYSINE
• EFFECT OF SUPPLEMENTATION OF LIMITING AMINO ACIDS ON TYROSINE TOXICITY IN RATS FED WHEAT GLUTEN DIETS
• EFFECT OF INDIVIDUAL AMINO ACID SUPPLEMENTS ON THE TOXICITY OF EXCESS TYROSINE IN RATS
• BENEFICIAL EFFECT OF METHIONINE AND THREONINE SUPPLEMENTS ON TYROSINE TOXICITY IN RATS
• Self-selection of histidine and arginine intake and the requirements for these amino acids in growing rats.
• Relationship between amino acid composition of diet and plasma cholesterol level in growing rats fed a high cholesterol diet.
• Effects of methionine and related compounds on plasma cholesterol level in rats fed a high cholesterol diet.
• Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats.
• Effect of individual amino acids on plasma cholesterol level in rats fed a high cholesterol diet.
• Dietary sulfur-containing amino acids and glycine as determinant factors in plasma cholesterol regulation in growing rats.
• Effect of dietary glycine on methionine metabolism in rats fed a high-methionine diet.
• Self-selection of phenylalanine in the rat.

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