BENEFICIAL EFFECT OF METHIONINE AND THREONINE SUPPLEMENTS ON TYROSINE TOXICITY IN RATS
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概要
- 論文の詳細を見る
The growth retardation and external pathological lesions that occur in rats fed a 10% casein diet containing 5% tyrosine could be alleviated by the supplementation of extra protein (20% casein) or 0.66% methionine plus 0.90% threonine (equivalent to the contents in a 20% casein, . respectively). Liver tyrosine aminotransferase activity is elevated by ingestion of excess tyrosine, but lowered by the supplementa tion of extra casein or methionine plus threonine. In rats fed a high tyrosine diet supplemented with methionine plus threonine, liver p-hydroxyphenylpyruvate hydroxylase activity was not higher than that of the 10% casein group, but liver homogentisate oxidase activity in creased significantly. When excess tyrosine was included in the 10 casein diet, free tyrosine concentrations in plasma, liver, muscle and brain were extremely elevated, but when the high tyrosine diet was sup plemented with extra casein or methionine: plus threonine, theirr plasma and tissues tyrosine concentrations lowered significantly. A large in, crease in total phenols, p-hydroxyphenylpyruvate and free tyrosine excretions in urine was produced in animals fed the high tyrosine-low protein diet, but these were lowered by the supplementation of methio nine and threonine to the diet.
- 財団法人 学会誌刊行センターの論文
著者
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片山 泰一
静岡大農 農化
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村松 敬一郎
Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture, Shiz
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山本 由喜子
Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture, Shiz
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片山 泰一
Laboratory of Foodd and Nutrition, Department of Aricultural Chemistry, Faculty of Agriculture, Shiz
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片山 泰一
Laboratory of Foodd and Nutrition, Department of Aricultural Chemistry, Faculty of Agriculture, Shizuoka University.
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山本 由喜子
Laboratory of Foodd and Nutrition, Department of Aricultural Chemistry, Faculty of Agriculture, Shizuoka University.
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山本 由喜子
Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture
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村松 敬一郎
Laboratory of Food and Nutrition, Department of Agricultural Chemistry, Faculty of Agriculture
関連論文
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- SUPPLEMENTAL EFFECT OF LYSINE ON GROWTH DEPRESSION OF RATS FED WHEAT GLUTEN DIETS CONTAINING EXCESSIVE AMOUNT OF SOME INDIVIDUAL AMINO ACIDS
- THE RELATIONSHIP BETWEEN WEIGHT GAIN AND FREE AMINO ACID CONCENTRATION OF PLASMA AND LIVER IN RATS FED A DIET SUPPLEMENTED WITH VARIOUS AMOUNTS OF LYSINE
- EFFECT OF SUPPLEMENTATION OF LIMITING AMINO ACIDS ON TYROSINE TOXICITY IN RATS FED WHEAT GLUTEN DIETS
- EFFECT OF INDIVIDUAL AMINO ACID SUPPLEMENTS ON THE TOXICITY OF EXCESS TYROSINE IN RATS
- BENEFICIAL EFFECT OF METHIONINE AND THREONINE SUPPLEMENTS ON TYROSINE TOXICITY IN RATS
- Self-selection of histidine and arginine intake and the requirements for these amino acids in growing rats.
- Relationship between amino acid composition of diet and plasma cholesterol level in growing rats fed a high cholesterol diet.
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- Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats.
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- Dietary sulfur-containing amino acids and glycine as determinant factors in plasma cholesterol regulation in growing rats.
- Effect of dietary glycine on methionine metabolism in rats fed a high-methionine diet.
- Self-selection of phenylalanine in the rat.