A case of amyloidosis appeared in gingiva of maxilla.

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A case of amyloidosis appeared in gingiva of maxilla was reported. The patient was a 81-year-old man complaining of unfitness of the dentures. In the oral cavity, the tumor was oval and elastic soft with pedicle, measuring 24×36×10mm in size, and located at the right upper molar region of the alveolar ridge. The surface of the tumor was dark-reddish, containing white flecks with keratinization at the margin of the tumor, and without spontaneous pain or tenderness. Radiographic examination showed a radiolucent region with irregular margins at the alveolar bone of the lesion. The tumor was resected under local anesthesia. Histopathologically, at the upper side of pedicle, much linear and massive hyaline substances were observed in submucosal layer. A histopathologic diagnosis of amyloidosis was made by congo red staining and electromicroscopic observation. An immunohistochemical study could not identify the types of amyloid proteins of this case.
社団法人日本口腔外科学会の論文