A case of squamous cell carcinoma of the buccal mucosa suspected of arising from the minor salivary glands.

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A squamous cell carcinoma of the buccal mucosa probably arising in the minor salivary glands was reported.<BR>About 1 month before presentation, a 65-year-old female noticed a tumor on the right buccal mucosa. It was superior to the right parotid papilla, hemospheric in form, measured 1.4 cm in diameter, and was mobile with an elastic firm consistency. The overlying mucosa was generally smooth. No abnormalities were detected by clinical examination. The tumor was removed along with the surrounding tissue. Histological examination revealed a well differentiated squamous cell carcinoma. Nodular carcinoma cell nests appeared immediately beneath the mucosa. The rests proliferated by replacing the minor salivary glands. Thickening (proliferation) of ductal epithelium was noted in the neighboring salivary glands.<BR>Neither recurrence nor metastasis have occurred as of 4 years and 3 months after surgery.