髄外性形質細胞腫が疑われた限局型若年性歯周炎の1例

概要

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A 21-year-old woman was referred to our hospital complaining of mobility of the upper left incisor. Her bilateral lower first molar had been removed 2 years ago due to periodontitis. The alveolar gingiva of the upper left incisor region showed tumorous swelling. Radiographic examination revealed irregular resorption of the alveolar bone in the same region. A biopsy was performed, and marked plasma cell infiltration was seen. However, no decision could be made regarding the diagnosis, and periodontitis and extramedullary plasmacytoma were suspected. Immunohistochemical staining for immunoglobulin showed that κ-and λ-positive cells were distributed equally. Due to this polyclonal production, inflammatory disease was suspected. Finally, a diagnosis of juvenile periodontitis was made. Immunohistochemical staining proved to be helpful in the diagnosis of abnormal plasma cell proliferation.