Gastric mucosal hemodynamics and oxygen sufficiency in patients with liver cirrhosis assessed by reflectance spectrophotometry.

概要

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The gastric mucosal hemodynamics and oxygen sufficiency in 46 patients with liver cirrhosis and in 45 normal controls were studied by reflectance spectrophotometry during endoscopy. The reflectance spectra were taken from 10 different regions in the stomach. The estimated mucosal blood volume was greater and the estimated oxygen saturation of hemoglobin in the gastric mucosal capillaries was lower in patients with liver cirrhosis than in normal controls. These results suggest the stasis and dilatation of capillaries of the stomach in cirrhotic patients.The mucosal blood volume and oxygen saturation of hemoglobin in the capillaries of the stomach was smaller in the cirrhotic patients with esophageal varices than without esophageal varices.In conclusion, the microcirculation of the gastric mucosa in patients with liver cirrhosis was disturbed, and this disturbance of microcirculation may play a role in the development of acute gastric mucosal lesions in these patients.
財団法人日本消化器病学会の論文