Carcinoma of the pancreas in association with pancreatolithiasis

概要

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Three cases of carcinoma of the pancreas associated with pancreatolithiasis are presented. The coexistence of the two conditions was found in three cases out of 54 cases of pancreatolithiasis (5.7%) and out of 106 cases of carcinoma of the pancreas (2.8%) in our series.Clinical features of cases of carcinoma of the pancreas in association with pancreatolithiasis were investigated by reviewing 12 well-documented cases including nine cases collected from Japanese literatures. In the 12 cases, the sex ratio was 11 men and one woman, and the average age of onset was 46.8 years old. Radiological findings of pancreatic stones obtained in nine cases did not show a pattern of diffuse small stones, but of multiple large stones. Considering from their clinical histories, it is suggested that pancreatolithiasis preceded onset of carcinoma of the pancreas in over half of cases.
財団法人日本消化器病学会の論文