Informatic identification of blocks of ordered nucleotide sequences in human chromosome 22
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概要
- 論文の詳細を見る
Using the draft sequence of human chromosome 22, blocks with a minimum length of 2K, in which combinations of bases are ordered to degrees higher than the rest, have been mathematically identified. Approximately 400 blocks are characterized with significantly low entropy values for combining 4-9 nucleotides each of the 4 types. These blocks span -3.5K bases on average, and altogether occupy 2.0-2.5% of this chromosome. The draft sequence extends from the end of the centromere to the beginning of the telomere, and the occupancy by identified blocks is highest near the two ends, and decreases while shifting nearer to the center.
- 日本学士院の論文
著者
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Suzuki Masashi
National Institute Of Advanced Industrial Science And Technology
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AMANO Naoki
National Institute of Advanced Industrial Science and Technology (AIST)
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MINEZAKI Yoshiaki
National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Center
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Minezaki Yoshiaki
National Inst. Genetics
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SUZUKI Masashi
National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Center
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