Localization of A:T and G:C basepairs in genomes of higher eukaryotes
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概要
- 論文の詳細を見る
By using a visual method of presenting DNA sequences (Makino, S., Amano, N., and Suzuki, M., 1999, Proc. Japan Acad. 75B, 311-316), genomic sequences of various organisms have been analyzed, including of a draft sequence of human genome (International Human Genome Sequencing Consortium, 2001, Nature 409, 860-921). It is concluded that, with an increase in the number of basepairs in a genome, a tendency becomes clearer for clustering of A:T pairs and G:C pairs separately into regions of 0.5-5K basepairs in length. It is likely that these regions have important functions for regulating transcription of the increasing number of genes coded and for organizing replication of the increasing length of genomic DNA.
- 日本学士院の論文
著者
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Suzuki Masashi
National Institute Of Advanced Industrial Science And Technology
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AMANO Naoki
National Institute of Advanced Industrial Science and Technology (AIST)
関連論文
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