An epidemiological study of HBvirus markers in Korean people in Hyogo prefecture.

概要

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In view of the high mortality rates of liver cirrhosis, and liver cancer in the cause of deaths among the Koreans living in Japan, the prevalences of HBvirus markers and liver tests such as sGOT, s-GPT ZTT were studied in 1473 Korean subjects living in Hyogo Prefecture. 1. The frequency of HBsAg was 5.1% and it revealed high peak at the forties. The value was apparently highter than that of Japanese. The frequency of anti-HBs was 9.1% and it revealed the gradual elevation according to age. The value was not so different from that of Japanese. 2. Liver tests revealed abnormality in 15.6% of HBsAg carriers, in 5.4% of anti-HBs positives, and in 2.5% of in both HBsAg and anti-HBs negatives. HBsAg carriers revealed high frequency of liver tests abnormality than the other two groups. 3. All 74 HBsAg carriers except one showed positive anti-HBs and 82.4% of them had titers above 210. In the majority of the anti-HBs positives, anti-HBc titer was low and two had titers above 210. Anti-HBc was positive in 2.6% of them who were negative in both HBsAg and Anti-HBs, and only one had titers above 210. 4. The frequencies of HBeAg and anti-HBe in HBsAg carriers were 62% and 31% respectively. The value of anti-HBe revealed gradual elevation accordind to age. It may be happened seroconversion from HBeAg to anti-HBe at latest in the thirties both in the males and females.
社団法人日本肝臓学会の論文