Hepatocellular carcinoma with esophageal varices: Combination of treatments and prognosis.

概要

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It has been very difficult to manage hepatocellular carcinoma with esophageal varices. In this study, we reviewed 54 cases diagnosed hepatocellular carcinoma and esophageal varices almost simultaneously to discuss combination of treatments for the two disease.<BR>Treatments performed for hepatocellular carcinoma were partial hepatic resection (6 cases), TAE (15 cases), intraarterial infusion chemotherapy (hepatic artery, 7 cases), intraarterial infusion chemotherapy (abdominal aorta, 6 cases) and no treatment (16 cases). Treatments for esophageal varices were nonshunting operation (23 cases), endoscopic injection sclerotherapy (23 cases) and no treatment (8 cases). The overall one year survival rate and two were 61% and 41% respectively. Most important factors which determine the patients' prognosis were severity of hepatic dysfunction, clinical stage of hepatocellular carcinoma, degree of portal invasion and history of variceal bleeding. Combination of at least two treatments for both diseases is essential for better prognosis.
社団法人日本肝臓学会の論文